NDUFS3 Recombinant Rabbit Monoclonal Antibody [JU10-32]

About this product

NDUFS3 (NADH dehydrogenase ubiquinone iron-sulfur protein 3) is one of about 45 subunits comprising complex I of the oxidative phosphorylation electron transport chain. The multisubunit NADH: ubiquinone oxidoreductase (complex I) is the first enzyme complex in the electron transport chain of the mitochondria. NDUFS3 is the last subunit of the seven subunits that make up the core of complex I. Through use of chaotropic agents, complex I can be separated into three different fractions: a flavoprotein fraction, an iron-sulfur protein (IP) fraction, and a hydrophobic protein (HP) fraction. The IP fraction includes NDUFS1-7. NDUFS3 contains a highly conserved casein kinase II phosphorylation site. Mutations in the NDUFS3 gene may cause optic atrophy, Leigh syndrome and complex I deficiency.

Specifications

Catalog number

ET1706-07

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CI 30 antibody CI 30KD antibody CI-30kD antibody Complex I 30KD antibody Complex I 30kDa subunit antibody COMPLEX I, MITOCHONDRIAL RESPIRATORY CHAIN, 30-KD SUBUNIT antibody Complex I-30kD antibody mitochondrial antibody NADH coenzyme Q reductase antibody NADH dehydrogenase (ubiquinone) Fe S protein 3 30kDa antibody NADH dehydrogenase [ubiquinone] iron sulfur protein 3 mitochondrial antibody NADH dehydrogenase [ubiquinone] iron-sulfur protein 3 antibody NADH dehydrogenase ubiquinone 30 kDa subunit antibody NADH-ubiquinone oxidoreductase 30 kDa subunit antibody NADH-Ubiquinone Oxidoreductase Fe-S Protein 3 antibody NDUFS3 antibody NDUS3_HUMAN antibody

Abbreviation

CI-30kD, NDUFS3

Swiss Prot

O75489 Human

Cellular Locus

Mitochondrion inner membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human NDUFS3 aa 215-264 / 264.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell, IF-Tissue, IP

Positive Control

HepG2 lysates, MCF-7, human colon carcinoma tissue, human kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500;IHC-P: 1:50;IF-Cell: 1:50;IP: 1:10-1:50

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 30 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes