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![LOXL2 Recombinant Rabbit Monoclonal Antibody [JU32-53] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8e061270361ea82550/imageurl/et1706-11.webp)
Product details
Catalog number ET1706-11
Price for ET1706-11
Size / count 100 µL
Lysyl oxidase homolog 2 is an enzyme that in humans is encoded by the LOXL2 gene.This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.LOXL2 can also crosslink collagen type IV and hence influence the sprouting of new blood vessels. LOXL2 is an enzyme that is up-regulated in several types of cancer and is associated with a poorer prognosis.LOXL2 changes the structure of histones (proteins that are attached to DNA) and thus changes the shape of the cells, making it easier for the cancer cells to metastasize.
The catalog number for LOXL2 Recombinant Rabbit Monoclonal Antibody [JU32-53] is ET1706-11.
LOXL2 Recombinant Rabbit Monoclonal Antibody [JU32-53] is available in the following size(s): 100 µL.
LOXL2 Recombinant Rabbit Monoclonal Antibody [JU32-53] is currently made to order / not held in immediate stock. Contact us for lead time.
Lysyl oxidase homolog 2 is an enzyme that in humans is encoded by the LOXL2 gene.This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalys
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
