SDHB Recombinant Rabbit Monoclonal Antibody [JU02-33] — image 1 of 3

Product details

SDHB Recombinant Rabbit Monoclonal Antibody [JU02-33]

Catalog number ET1706-30

Price for ET1706-30

Size / count 100 µL

About this product

In aerobic respiration reactions, succinate dehydrogenase (SDH) catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol. Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. Mutations to these subunits cause mitochondrial dysfunction, corresponding to several distinct disorders. Mutations in the membrane bound components may cause hereditary paraganglioma, while SDHA mutations associate with juvenile encephalopathy as well as Leigh syndrome, a severe neurological disorder. Inactivating mutations in SDHB correlate with inherited, but not necessarily sporadic, cases of pheochromocytoma.

Specifications

Catalog number: ET1706-30
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CWS2 antibody DHSB_HUMAN antibody FLJ92337 antibody Ip antibody Iron sulfur subunit antibody Iron sulfur subunit of complex II antibody Iron-sulfur subunit of complex II antibody mitochondrial antibody PGL 4 antibody PGL4 antibody SDH 1 antibody SDH antibody SDH1 antibody SDH2 antibody SDH2, homolog of antibody SdhB antibody SDHIP antibody Succinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrial antibody Succinate dehydrogenase [ubiquinone] iron sulfur subunit antibody Succinate dehydrogenase [ubiquinone] iron-sulfur subunit antibody succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial antibody Succinate Dehydrogenase 1 Iron Sulfur Subunit antibody Succinate Dehydrogenase 2, S. cerevisiae, homolog of antibody Succinate dehydrogenase complex iron sulfur subunit B antibody Succinate dehydrogenase complex subunit B iron sulfur antibody Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein antibody succinate dehydrogenase complex, subunit B, iron sulfur (Ip) antibody Succinate dehydrogenase iron sulfur protein antibody
Abbreviation: Ip, SDHB, SDH, SDH1
Swiss Prot: P21912 Human, Q9CQA3 Mouse, P21913 Rat
Cellular Locus: Mitochondrion. Mitochondrion inner membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human SDHB aa 201-250 / 280.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: HepG2 cell lysate, Mouse spleen tissue lysate, Rat spleen tissue lysate, Rat liver tissue lysate, Human liver tissue lysate, human kidney tissue, mouse kidney tissue, rat kidney tissue, human liver tissue, human colon carcinoma tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IHC-P: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 32 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for SDHB Recombinant Rabbit Monoclonal Antibody [JU02-33]?

The catalog number for SDHB Recombinant Rabbit Monoclonal Antibody [JU02-33] is ET1706-30.

What sizes are available for SDHB Recombinant Rabbit Monoclonal Antibody [JU02-33]?

SDHB Recombinant Rabbit Monoclonal Antibody [JU02-33] is available in the following size(s): 100 µL.

Is SDHB Recombinant Rabbit Monoclonal Antibody [JU02-33] in stock?

SDHB Recombinant Rabbit Monoclonal Antibody [JU02-33] is currently made to order / not held in immediate stock. Contact us for lead time.

What is SDHB Recombinant Rabbit Monoclonal Antibody [JU02-33] used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.