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Product details

LOX Recombinant Rabbit Monoclonal Antibody [JU30-23]

Catalog number ET1706-31

Price for ET1706-31

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Size / count 100 µL

About this product

The lysyl oxidase family of extracellular proteins includes LOX and four LOX-like enzymes, which are responsible for the deamination of peptidyl lysine residues of collagens and elastin. They also catalyze inter- and intra-crosslinking reactions. Overexpression of LOX may cause severe fibrotic degeneration due to its high resistance to degradative enzymes. Procollagen C-proteinase activity processes LOX from a precursor protein to a mature form. Activation of LOX occurs in normal developing and adult skin, and alterations in LOX expression and activity are associated with skin aging and senescence. LOX is crucial for development of the cardiovascular and respiratory systems. In addition, LOX plays a role in cancer, wound healing, as well as cell motility, chemotaxis and differentiation.

Specifications

Catalog number
ET1706-31
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
lox antibody LYOX antibody LYOX_HUMAN antibody Lysyl oxidase antibody MGC105112 antibody Protein lysine 6 oxidase antibody Protein-lysine 6-oxidase antibody
Abbreviation
LOX
Swiss Prot
P28300 Human, P28301 Mouse, P16636 Rat
Cellular Locus
Secreted, extracellular space.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Zebrafish
Immunogen
Synthetic peptide within Human LOX aa 368-417 / 417.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC, IF-Tissue
Positive Control
PC-3M cell lysate, Jurkat cell lysate, Mouse lung tissue lysate, Rat lung tissue lysate, Mouse brain tissue lysate, Rat brain tissue lysate, zebrafish tissue lysates, Jurkat, human stomach cancer tissue, human kidney tissue, mouse kidney tissue, rat kidney tissue, zebrafish tissue lysates.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IF-Cell: 1:1,000 ;IHC-P: 1:200-1:1,000 ;FC: 1:1,000 ;IF-Tissue: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 47 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for LOX Recombinant Rabbit Monoclonal Antibody [JU30-23]?

The catalog number for LOX Recombinant Rabbit Monoclonal Antibody [JU30-23] is ET1706-31.

What sizes are available for LOX Recombinant Rabbit Monoclonal Antibody [JU30-23]?

LOX Recombinant Rabbit Monoclonal Antibody [JU30-23] is available in the following size(s): 100 µL.

Is LOX Recombinant Rabbit Monoclonal Antibody [JU30-23] in stock?

LOX Recombinant Rabbit Monoclonal Antibody [JU30-23] is currently made to order / not held in immediate stock. Contact us for lead time.

What is LOX Recombinant Rabbit Monoclonal Antibody [JU30-23] used for?

The lysyl oxidase family of extracellular proteins includes LOX and four LOX-like enzymes, which are responsible for the deamination of peptidyl lysine residues of collagens and elastin. They also catalyze inter- and intra-crosslinking reactions. Overexpression of LOX may cause severe fibrotic degen

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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