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![Wnt5a Recombinant Rabbit Monoclonal Antibody [JU30-30] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81c63/imageurl/et1706-33.webp)
Product details
Catalog number ET1706-33
Price for ET1706-33
Size / count 100 µL
The Wnt genes belong to a family of protooncogenes with at least 13 known members that are expressed in species ranging from Drosophila to man. The name Wnt denotes the relationship of this family to the Drosophila segment polarity gene "wingless" and to its vertebrate ortholog, Int1, a mouse protooncogene. Transcription of Wnt family genes appears to be developmentally regulated in a precise temporal and spatial manner. The Wnt genes encode cysteine-rich putative glycoproteins, which have features typical of secreted growth factors. Northern blot analysis detects expression of Wnt-5a in brain, lung, and heart. At least five distinct Wnt-5a transcripts are observed, which are due to transcript variability 5-prime to the initiation methionine. In situ hybridization detects a complex spatial and temporal pattern of Wnt-5a in the mouse, including expression in the developing central nervous system, limbs, facial processes, and the posterior region of the fetus. Human frizzled-5 is the receptor for the Wnt-5a ligand. It is suggested that Wnt-5a augments primitive hematopoietic development in vivo and represents an in vivo regulator of hematopoietic stem cell function in the human.
The catalog number for Wnt5a Recombinant Rabbit Monoclonal Antibody [JU30-30] is ET1706-33.
Wnt5a Recombinant Rabbit Monoclonal Antibody [JU30-30] is available in the following size(s): 100 µL.
Wnt5a Recombinant Rabbit Monoclonal Antibody [JU30-30] is currently made to order / not held in immediate stock. Contact us for lead time.
The Wnt genes belong to a family of protooncogenes with at least 13 known members that are expressed in species ranging from Drosophila to man. The name Wnt denotes the relationship of this family to the Drosophila segment polarity gene "wingless" and to its vertebrate ortholog, Int1, a mouse protoo
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
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