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Product details

Drosha Recombinant Rabbit Monoclonal Antibody [JU33-01]

Catalog number ET1706-34

Price for ET1706-34

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Size / count 100 µL

About this product

The ribonuclease III superfamily represents a structurally distinct group of double-strand-specific endonucleases with essential roles in RNA maturation, RNA decay, and gene silencing. Initial cleavage of microRNAs is catalysed by Drosha, a nuclease of the RNase III family, which acts on primary miRNA transcripts (pri-miRNAs) in the nucleus. Human Drosha is a component of two multi-protein complexes. The larger complex contains multiple classes of RNA-associated proteins including RNA helicases, proteins that bind double-stranded RNA, novel heterogeneous nuclear ribonucleoproteins and the Ewing's sarcoma family of proteins. The smaller complex is composed of Drosha and the double-stranded-RNA-binding protein, DGCR8.

Specifications

Catalog number
ET1706-34
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
DROSHA antibody Drosha double stranded RNA specific endoribonuclease antibody Drosha ribonuclease type III antibody Etohi2 antibody HSA242976 antibody Nuclear RNase III Drosha antibody p241 antibody Protein Drosha antibody Putative protein p241 which interacts with transcription factor Sp1 antibody Putative ribonuclease III antibody RANSE3L antibody Ribonuclease 3 antibody Ribonuclease III antibody Ribonuclease III nuclear antibody Ribonuclease type III nuclear antibody RibonucleaseIII antibody RN 3 antibody RN3 antibody RNase 3 antibody RNase III antibody RNase3 antibody RNASE3L antibody RNaseIII antibody RNASEN antibody RNC_HUMAN antibody
Abbreviation
RNase III, DROSHA, RN3, RNASE3L, RNASEN
Swiss Prot
Q9NRR4 Human
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human Drosha aa 30-79 / 1,374.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control
Hela cell lysate, SiHa cell lysate, K562 cell lysates, A549, Hela, LOVO, human kidney tissue, human placenta tissue, Jurkat.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
159 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Drosha Recombinant Rabbit Monoclonal Antibody [JU33-01]?

The catalog number for Drosha Recombinant Rabbit Monoclonal Antibody [JU33-01] is ET1706-34.

What sizes are available for Drosha Recombinant Rabbit Monoclonal Antibody [JU33-01]?

Drosha Recombinant Rabbit Monoclonal Antibody [JU33-01] is available in the following size(s): 100 µL.

Is Drosha Recombinant Rabbit Monoclonal Antibody [JU33-01] in stock?

Drosha Recombinant Rabbit Monoclonal Antibody [JU33-01] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Drosha Recombinant Rabbit Monoclonal Antibody [JU33-01] used for?

The ribonuclease III superfamily represents a structurally distinct group of double-strand-specific endonucleases with essential roles in RNA maturation, RNA decay, and gene silencing. Initial cleavage of microRNAs is catalysed by Drosha, a nuclease of the RNase III family, which acts on primary miR

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

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