WASL Recombinant Rabbit Monoclonal Antibody [JU07-31]

About this product

This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension. Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Involved in mitosis and cytokinesis, via its role in the regulation of actin polymerization. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression..

Specifications

Catalog number

ET1706-39

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

WASP family, verprolin homology domain-containing protein 1 antibody WASP family member 1 antibody FLJ31482 antibody homology of dictyostelium scar 1 antibody KIAA0269 antibody Protein WAVE-1 antibodyv Protein WAVE1 antibody scar, Dictyostelium, homology of, 1 antibody SCAR1 antibody Similar to a plant extensin like protein antibody Verprolin homology domain containing protein 1 antibody Verprolin homology domain-containing protein 1 antibody WAS protein family, member 1 antibody Wasf1 antibody WASF1_HUMAN antibody WASL antibody WASP family 1 antibody WASP family protein member 1 antibody WASP family, verprolin homology domain-containing protein antibody WAVE antibody WAVE1 antibody Wiskott Aldrich syndrome protein family member 1 antibody Wiskott-Aldrich syndrome protein family member 1 antibody

Abbreviation

N-WASP

Swiss Prot

O00401 Human, Q91YD9 Mouse

Cellular Locus

Cytoplasm, cytoskeleton. Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Synthetic peptide within Human WASL aa 401-450 / 505.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

Human serum, SH-SY5Y, SK-Br-3, human colon cancer tissue, human kidney tissue, human spleen tissue, mouse colon tissue, mouse brain tissue, K562.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

55 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes