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Product details

GPX4 Recombinant Rabbit Monoclonal Antibody [JU11-31]

Catalog number ET1706-45

Discontinued

Price for ET1706-45

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Size / count 100 µL

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About this product

Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1-8). GPx-1, Gpx-2 and Gpx-3 exist as homotetramers. Gpx-4 has a high tendancy to form high molecular weight oligomers.

Specifications

Catalog number
ET1706-45
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9000-83-3
Product Name Alternative
Glutathione peroxidase 4 antibody GPX 4 antibody GPX-4 antibody GPX4 antibody GPX4_HUMAN antibody GSHPx-4 antibody MCSP antibody mitochondrial antibody PHGPx antibody Phospholipid hydroperoxidase antibody Phospholipid hydroperoxide glutathione peroxidase antibody Phospholipid hydroperoxide glutathione peroxidase mitochondrial antibody snGPx antibody snPHGPx antibody Sperm nucleus glutathione peroxidase antibody
Abbreviation
PHGPx, GPx-4, GSHPx-4
Swiss Prot
P36969 Human, O70325 Mouse, P36970 Rat
Cellular Locus
Mitochondrion, Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Zebrafish
Immunogen
Synthetic peptide within Human GPX4 aa 23-72 / 197.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
HeLa cell lysate, A549 cell lysate, HepG2 cell lysate, U-937 cell lysate, HEK-293 cell lysate, mouse testis tissue lysate, rat testis tissue lysate, mouse kidney tissue lysate, rat kidney tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, zebrafish tissue lysates, HEK-293, rat epididymis tissue, human kidney tissue, mouse testis tissue, MCF-7, PC-3M, LOVO.
Concentration
1 mg/mL
Dilution
WB: 1:10,000 ;IHC-P: 1:200-1:1,000 ;IF-Cell: 1:50-1:200 ;FC:1: 10,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 22 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for GPX4 Recombinant Rabbit Monoclonal Antibody [JU11-31]?

The catalog number for GPX4 Recombinant Rabbit Monoclonal Antibody [JU11-31] is ET1706-45.

Is GPX4 Recombinant Rabbit Monoclonal Antibody [JU11-31] in stock?

GPX4 Recombinant Rabbit Monoclonal Antibody [JU11-31] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GPX4 Recombinant Rabbit Monoclonal Antibody [JU11-31] used for?

Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in hig

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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