Cullin 4a Recombinant Rabbit Monoclonal Antibody [JU07-33] — image 1 of 3

Product details

Cullin 4a Recombinant Rabbit Monoclonal Antibody [JU07-33]

Catalog number ET7106-56

Price for ET7106-56

Size / count 100 µL

About this product

Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. DCX (DET1-COP1) directs ubiquitination of JUN. DCX (DDB2) directs ubiquitination of XPC. DCX (DDB2) ubiquitinates histones H3-H4 and is required for efficient histone deposition during replication-coupled (H3.1) and replication-independent (H3.3) nucleosome assembly, probably by facilitating the transfer of H3 from ASF1A/ASF1B to other chaperones involved in histone deposition.

Specifications

Catalog number: ET7106-56
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 2810470J21Rik antibody AW495282 antibody CUL 4A antibody CUL-4A antibody Cul4a antibody Cul4a protein antibody CUL4A_HUMAN antibody Cullin-4A antibody MGC36573 antibody MGC64071 antibody
Abbreviation: CUL-4A, CUL4A
Swiss Prot: Q13619 Human
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human Cullin 4a aa 710-759 / 759.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Hela cell lysate, SiHa cell lysate, A431, HUVEC, human liver carcinoma tissue, human cervix tissue, human colon carcinoma tissue, human breast carcinoma tissue, human kidney tissue, Hela.
Concentration: 1 mg/mL
Dilution: WB: 1:500-2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 88 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Cullin 4a Recombinant Rabbit Monoclonal Antibody [JU07-33]?

The catalog number for Cullin 4a Recombinant Rabbit Monoclonal Antibody [JU07-33] is ET7106-56.

What sizes are available for Cullin 4a Recombinant Rabbit Monoclonal Antibody [JU07-33]?

Cullin 4a Recombinant Rabbit Monoclonal Antibody [JU07-33] is available in the following size(s): 100 µL.

Is Cullin 4a Recombinant Rabbit Monoclonal Antibody [JU07-33] in stock?

Cullin 4a Recombinant Rabbit Monoclonal Antibody [JU07-33] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cullin 4a Recombinant Rabbit Monoclonal Antibody [JU07-33] used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.