SCGB1A1 Recombinant Rabbit Monoclonal Antibody [JU34-03]

About this product

SCGB1A1 also named CC10. Clara cell 10 (CC10) protein, a homologue of rabbit uteroglobin, is a phospholipase A2 inhibitor. CC10 is regulated by AP-1, octamer, and hepatocyte nuclear factor-3 (HNF-3) family transcription factors. CC10 expression changes in relation to the ovarian menstrual cycle, and expression in human endometrium may be stimulated by progesterone, suggesting that CC10 may regulate eicosanoid levels in the human uterus. CC10 is expressed in nonciliated airway epithelial cells in the lung and in urogenital secretions. CC10 is involved in modulating inflammation in airway passages and may play a role in asthma. Overexpression of CC10 in the non-small cell lung cancer cell line A549 was shown to result in the near absence of MMP-2 and MMP-9 matrix metalloproteinases and a reduction in invasiveness, indicating that loss of CC10 may contribute to carcinogenesis.

Specifications

Catalog number

ET7106-71

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Blastokinin antibody CC10 antibody CC16 antibody CCPBP antibody CCSP antibody Clara cell phospholipid binding protein antibody Clara cell phospholipid-binding protein antibody Clara cell specific 10 kD protein antibody Clara cells 10 kDa secretory protein antibody OTTHUMP00000236107 antibody SCGB1A1 antibody Secretoglobin family 1A member 1 antibody Secretoglobin, family 1A, member 1 (uteroglobin) antibody UG antibody UGB antibody UP-1 antibody UP1 antibody Urinary protein 1 antibody Urine protein 1 antibody UTER_HUMAN antibody Uteroglobin antibody

Abbreviation

CCPBP, CC10, UP-1, UP1, Urine protein 1, SCGB1A1, CC10, CCSP, UGB

Swiss Prot

P11684 Human, Q06318 Mouse, P17559 Rat

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human SCGB1A1 aa 42-91 / 91.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, FC, IHC-P

Positive Control

Mouse lung tissue lysate, human lung tissue lysate, A549 cell lysate, A431, A549, HUVEC, human trachea tissue, mouse lung tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;FC: 1:50-1:100 ;IHC-P: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 10 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes