PCAF Recombinant Rabbit Monoclonal Antibody [JU88-63] — image 1 of 2

Product details

PCAF Recombinant Rabbit Monoclonal Antibody [JU88-63]

Catalog number ET7106-79

Price for ET7106-79

Size / count 100 µL

About this product

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessiblity to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1) and HDAC2 (also designated mammalian RPD3), both of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases.

Specifications

Catalog number: ET7106-79
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CAF antibody CREBBP associated factor antibody GCN5 antibody GCN5L antibody GCN5L1 antibody Histone acetylase PCAF antibody Histone acetyltransferase KAT2B antibody Histone acetyltransferase PCAF antibody K (lysine) acetyltransferase 2B antibody KAT2B antibody KAT2B_HUMAN antibody Lysine acetyltransferase 2B antibody P antibody P/CAF antibody p300/CBP associated factor antibody P300/CBP-associated factor antibody Pcaf antibody
Abbreviation: Histone acetylase PCAF, P/CAF, KAT2B, PCAF
Swiss Prot: Q92831 Human, Q568Z2 Rat
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human PCAF aa 121-211 .
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IP, FC
Positive Control: HeLa cell lysates, Hela.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;FC: 1:50-1:100 ;IP: 1:10-1:50
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 93 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for PCAF Recombinant Rabbit Monoclonal Antibody [JU88-63]?

The catalog number for PCAF Recombinant Rabbit Monoclonal Antibody [JU88-63] is ET7106-79.

What sizes are available for PCAF Recombinant Rabbit Monoclonal Antibody [JU88-63]?

PCAF Recombinant Rabbit Monoclonal Antibody [JU88-63] is available in the following size(s): 100 µL.

Is PCAF Recombinant Rabbit Monoclonal Antibody [JU88-63] in stock?

PCAF Recombinant Rabbit Monoclonal Antibody [JU88-63] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PCAF Recombinant Rabbit Monoclonal Antibody [JU88-63] used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.