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Product details

PCK1 Recombinant Rabbit Monoclonal Antibody [JU84-39]

Catalog number ET7106-81

Price for ET7106-81

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Size / count 100 µL

About this product

Normal adjustment to changes in blood glucose levels depends on insulin signaling as well as enzymes involved in the regulation of gluconeogenesis. Pathological changes to this process are central to the type 2 diabetes phenotype. Phosphoenolpyruvate carboxykinase (PEPCK) plays an important role in this process by stimulating hepatic glucose production. PEPCK expression increases in response to glucagon and glucocorticoids, while insulin suppresses expression. Modulation of the signals governing PEPCK levels present a potential therapeutic approach to the treatment of insulin resistance and consequently obesity. The cytosolic form of PEPCK, known as PEPCK-C, and the mitochondrial form, known as PEPCK-M, are encoded by two different nuclear genes in mouse, human and chicken.

Specifications

Catalog number
ET7106-81
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
cytosolic [GTP] antibody GTP antibody PCK1 antibody PCKGC_HUMAN antibody PEP carboxykinase antibody PEPCK-C antibody PEPCK1 antibody PEPCKC antibody Phosphoenolpyruvate carboxykinase 1 (soluble) antibody Phosphoenolpyruvate carboxykinase 1 antibody Phosphoenolpyruvate carboxykinase antibody Phosphoenolpyruvate carboxykinase, cytosolic [GTP] antibody Phosphoenolpyruvate carboxykinase, cytosolic antibody Phosphoenolpyruvate carboxylase antibody Phosphopyruvate carboxylase antibody
Abbreviation
PEPCK-C, PCK1, PEPCK1
Swiss Prot
P35558 Human
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human PCK1 aa 26-75 / 622.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
IF-Cell, IHC-P, WB
Positive Control
293T, HepG2, SH-SY5Y, human liver tissue, human kidney tissue.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:50-1:100 ;IHC-P: 1:200 ;WB: 1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
69 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for PCK1 Recombinant Rabbit Monoclonal Antibody [JU84-39]?

The catalog number for PCK1 Recombinant Rabbit Monoclonal Antibody [JU84-39] is ET7106-81.

What sizes are available for PCK1 Recombinant Rabbit Monoclonal Antibody [JU84-39]?

PCK1 Recombinant Rabbit Monoclonal Antibody [JU84-39] is available in the following size(s): 100 µL.

Is PCK1 Recombinant Rabbit Monoclonal Antibody [JU84-39] in stock?

PCK1 Recombinant Rabbit Monoclonal Antibody [JU84-39] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PCK1 Recombinant Rabbit Monoclonal Antibody [JU84-39] used for?

Normal adjustment to changes in blood glucose levels depends on insulin signaling as well as enzymes involved in the regulation of gluconeogenesis. Pathological changes to this process are central to the type 2 diabetes phenotype. Phosphoenolpyruvate carboxykinase (PEPCK) plays an important role in

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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