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![Protein Kinase D2 Recombinant Rabbit Monoclonal Antibody [JU08-33] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81bd7/imageurl/et7106-87.webp)
Product details
Catalog number ET7106-87
Price for ET7106-87
Size / count 100 µL
PKD2 (protein kinase D2), also known as PRKD2 or HSPC187, is a widely expressed protein belonging to the protein kinase D (PKD) family of serine/threonine kinases. In mammals, there are three members of the PKD family, namely PKC µ, PKD2 and PKC n, and each contain a homologous catalytic domain but differ in their tissue expression and subcellular localization. PKD family members are activated by G-protein-coupled receptors (GPCRs) and are known to participate in biological processes such as proliferation, apoptosis, migration, signal transduction and vesicle shedding. Shuttling between the nucleus and the cytoplasm, PKD2 contains one PH domain, one protein kinase domain and two phorbol-ester/DAG-type zinc fingers, and functions as a calcium-independent, phospholipid-dependent protein kinase. Upon activation of CCK-BR, PKD2 is phosphorylated by casein kinase I isoforms and subsequently accumulates in the nucleus. The result of the nuclear accumulation of PKD2 is the transcriptional activation of Nur77 and the nuclear exclusion of HDAC7. This suggests that PKD2 mediates CCK-BR-induced transcriptional activation.
The catalog number for Protein Kinase D2 Recombinant Rabbit Monoclonal Antibody [JU08-33] is ET7106-87.
Protein Kinase D2 Recombinant Rabbit Monoclonal Antibody [JU08-33] is available in the following size(s): 100 µL.
Protein Kinase D2 Recombinant Rabbit Monoclonal Antibody [JU08-33] is currently made to order / not held in immediate stock. Contact us for lead time.
PKD2 (protein kinase D2), also known as PRKD2 or HSPC187, is a widely expressed protein belonging to the protein kinase D (PKD) family of serine/threonine kinases. In mammals, there are three members of the PKD family, namely PKC µ, PKD2 and PKC n, and each contain a homologous catalytic domain but
Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.
