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Product details

GABA B Receptor 2 Recombinant Rabbit Monoclonal Antibody [JU31-32]

Catalog number ET7106-88

Price for ET7106-88

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Size / count 100 µL

About this product

In the central nervous system (CNS), gamma-aminobutyric acid (GABA) is the main main inhibitory neurotransmitter that functions to regulate neuronal firing. GABA exerts its effects through two different kinds of receptors: ionotropic receptors (GABAA R and GABAC R), which produce fast inhibitory signals, and metabotropic receptors (GABAB R), which produce slow inhibitory signals. The GABAB R receptor is a heterodimer that consists of two multi-pass membrane proteins, designated GABAB R1 and GABAB R2, both of which belong to the G protein-coupled receptor family and are highly expressed in brain tissue. Together, GABAB R1 and GABAB R2 play a crucial role in the fine-tuning of inhibitory synaptic transmissions and are implicated in slow wave sleep, muscle relaxation, hippocampal long-term potentiation and antinociception events. Both GABAB R1 and GABAB R2 are regulated by G proteins that have a variety of functions, including activation of potassium channels, inhibition of adenylyl cyclase (A cyclase) activity and modulation of inositol phospholipid hydrolysis.

Specifications

Catalog number
ET7106-88
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
BcDNA:GH07312 antibody CG6706 antibody CT20836 antibody D Gaba2 antibody FLJ36928 antibody G protein coupled receptor 51 antibody G-protein coupled receptor 51 antibody GAB B R2 antibody GABA B R2 antibody GABA B receptor 2 antibody GABA-B receptor 2 antibody GABA-B-R2 antibody GABA-BR2 antibody GABAB R2 antibody GABABR 2 antibody GABABR2 antibody GABB R2 antibody GABBR 2 antibody Gabbr2 antibody GABR2_HUMAN antibody Gamma aminobutyric acid B receptor 2 antibody Gamma aminobutyric acid GABA B receptor 2 antibody Gamma aminobutyric acid type B receptor subunit 2 antibody Gamma-aminobutyric acid type B receptor subunit 2 antibody Gb 2 antibody Gb2 antibody GH07312 antibody GPR 51 antibody GPR51 antibody GPRC 3B antibody GPRC3B antibody HG 20 antibody HG20 antibody HRIHFB2099 antibody Metabotropic GABA B receptor subtype 2 antibody OTTHUMP00000021776 antibody OTTHUMP00000063797 antibody R2 SUBUNIT antibody
Abbreviation
GABA-B receptor 2, GABA-B-R2, GABA-BR2, GABABR2, Gb2, Gabbr2, Gm425, Gpr51
Swiss Prot
O75899 Human, Q80T41 Mouse, O88871 Rat
Cellular Locus
Plasma membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within C-terminal Human GABA B Receptor 2 .
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC, IF-Cell, IHC-Fr, IF-Tissue
Positive Control
Mouse brain tissue lysate, rat brain tissue lysate, mouse brain tissue, rat brain tissue, mouse cerebellum tissue, SH-SY-5Y.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IF-Cell: 1:50-1:100 ;IHC-Fr: 1:500 ;IF-Tissue: 1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 106 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for GABA B Receptor 2 Recombinant Rabbit Monoclonal Antibody [JU31-32]?

The catalog number for GABA B Receptor 2 Recombinant Rabbit Monoclonal Antibody [JU31-32] is ET7106-88.

What sizes are available for GABA B Receptor 2 Recombinant Rabbit Monoclonal Antibody [JU31-32]?

GABA B Receptor 2 Recombinant Rabbit Monoclonal Antibody [JU31-32] is available in the following size(s): 100 µL.

Is GABA B Receptor 2 Recombinant Rabbit Monoclonal Antibody [JU31-32] in stock?

GABA B Receptor 2 Recombinant Rabbit Monoclonal Antibody [JU31-32] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GABA B Receptor 2 Recombinant Rabbit Monoclonal Antibody [JU31-32] used for?

In the central nervous system (CNS), gamma-aminobutyric acid (GABA) is the main main inhibitory neurotransmitter that functions to regulate neuronal firing. GABA exerts its effects through two different kinds of receptors: ionotropic receptors (GABAA R and GABAC R), which produce fast inhibitory sig

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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