Cellular Apoptosis Susceptibility Recombinant Rabbit Monoclonal Antibody [JU34-33] — image 1 of 3

Product details

Cellular Apoptosis Susceptibility Recombinant Rabbit Monoclonal Antibody [JU34-33]

Catalog number ET7106-90

Price for ET7106-90

Size / count 100 µL

About this product

Cellular apoptosis susceptibility protein (CAS), also called Exportin 2, is a 971 amino acid member of the CSE1 family. CAS mediates Importin α re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm. In the nucleus, CAS binds cooperatively to Importin α and to the GTPase Ran in its GTP-bound (active) form. This complex binds to nucleoporins as it docks to the nuclear pore complex. Once in the cytoplasm, the complex dissociates and Importin α is released and CAS returns to the nuclear compartment and the process begins anew. CAS can be detected highly in proliferating cells. Three isoforms of CAS have been named due to alternative splicing. Isoform 1 is the full length, 971 amino acid protein. Isoform 2 contains an alternative sequence for amino acids 190-195 and is missing amino acids 196-971. Isoform 3 contains an alternative sequence for amino acids 943-945 and is missing amino acids 946-971.

Specifications

Catalog number: ET7106-90
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CAS antibody Cellular apoptosis susceptibility protein antibody Chromosome segregation 1 (yeast homolog) like antibody Chromosome segregation 1 Like antibody Chromosome segregation 1 like protein antibody Chromosome segregation 1-like protein antibody Chromosome segregation gene CSE1 antibody CSE 1 antibody CSE 1 chromosome segregation 1 like antibody CSE 1 chromosome segregation 1 like protein antibody CSE 1L antibody CSE1 antibody CSE1 chromosome segregation 1 like (yeast) antibody CSE1 chromosome segregation 1 like antibody CSE1 chromosome segregation 1 like protein antibody CSE1L antibody Exp 2 antibody Exp2 antibody Exportin 2 antibody Exportin-2 antibody Exportin2 antibody Importin alpha re exporter antibody Importin-alpha re-exporter antibody MGC117283 antibody MGC130036 antibody MGC130037 antibody XPO 2 antibody XPO2 antibody XPO2_HUMAN antibody
Abbreviation: Exp2, CSE1L, CAS, XPO2
Swiss Prot: P55060 Human, Q9ERK4 Mouse
Cellular Locus: Cytoplasm. Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human Cellular Apoptosis Susceptibility aa 860-971 / 971.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control: SW480 cell lysate, MCF7 cell lysate, SK-Br-3 cell lysate, SiHa cell lysate, PC-3M cell lysate, HeLa cell lysate, Ramos cell lysate, mouse testis tissue lysate, LOVO, PC-3M, SH-SY5Y, human colon carcinoma tissue, mouse testis tissue, LOVO.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:200-1:1,000 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 110 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Cellular Apoptosis Susceptibility Recombinant Rabbit Monoclonal Antibody [JU34-33]?

The catalog number for Cellular Apoptosis Susceptibility Recombinant Rabbit Monoclonal Antibody [JU34-33] is ET7106-90.

What sizes are available for Cellular Apoptosis Susceptibility Recombinant Rabbit Monoclonal Antibody [JU34-33]?

Cellular Apoptosis Susceptibility Recombinant Rabbit Monoclonal Antibody [JU34-33] is available in the following size(s): 100 µL.

Is Cellular Apoptosis Susceptibility Recombinant Rabbit Monoclonal Antibody [JU34-33] in stock?

Cellular Apoptosis Susceptibility Recombinant Rabbit Monoclonal Antibody [JU34-33] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cellular Apoptosis Susceptibility Recombinant Rabbit Monoclonal Antibody [JU34-33] used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.