GIT1 Recombinant Rabbit Monoclonal Antibody [JU33-39] — image 1 of 3

Product details

GIT1 Recombinant Rabbit Monoclonal Antibody [JU33-39]

Catalog number ET7106-91

Price for ET7106-91

Size / count 100 µL

About this product

Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade. GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking. GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling.

Specifications

Catalog number: ET7106-91
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: ARF GAP GIT1 antibody ARF GTPase activating protein GIT1 antibody ARF GTPase-activating protein GIT1 antibody CAT 1 antibody CAT-1 antibody CaT1 antibody Cool associated and tyrosine phosphorylated protein 1 antibody Cool-associated and tyrosine-phosphorylated protein 1 antibody G protein coupled receptor kinase interacting ArfGAP 1 antibody G protein coupled receptor kinase interactor 1 antibody G protein-coupled receptor kinase-interactor 1 antibody GIT1 antibody GIT1_HUMAN antibody GRK interacting protein 1 antibody GRK-interacting protein 1 antibody
Abbreviation: ARF GAP GIT1, CAT-1, CAT1, GIT1
Swiss Prot: Q9Y2X7 Human, Q68FF6 Mouse, Q9Z272 Rat
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human GIT1 aa 79-297 .
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: A549 cell lysates, human colon carcinoma tissue, human pancreas tissue, mouse fallopian tubes, rat brain tissue, A549, mouse small intestine tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:50-1:400 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 84 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for GIT1 Recombinant Rabbit Monoclonal Antibody [JU33-39]?

The catalog number for GIT1 Recombinant Rabbit Monoclonal Antibody [JU33-39] is ET7106-91.

What sizes are available for GIT1 Recombinant Rabbit Monoclonal Antibody [JU33-39]?

GIT1 Recombinant Rabbit Monoclonal Antibody [JU33-39] is available in the following size(s): 100 µL.

Is GIT1 Recombinant Rabbit Monoclonal Antibody [JU33-39] in stock?

GIT1 Recombinant Rabbit Monoclonal Antibody [JU33-39] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GIT1 Recombinant Rabbit Monoclonal Antibody [JU33-39] used for?

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.