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Product details

DKC1 Recombinant Rabbit Monoclonal Antibody [JU34-32]

Catalog number ET7106-93

Price for ET7106-93

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Size / count 100 µL

About this product

Isoform 1: Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. Isoform 3: Promotes cell to cell and cell to substratum adhesion, increases the cell proliferation rate and leads to cytokeratin hyper-expression (when overexpressed in HeLa cells).

Specifications

Catalog number
ET7106-93
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CBF5 antibody CBF5 homolog antibody Cbf5p homolog antibody DKC 1 antibody DKC antibody Dkc1 antibody DKC1_HUMAN antibody DKCX antibody Dyskeratosis congenita 1 antibody Dyskeratosis congenita 1 dyskerin antibody Dyskerin antibody H/ACA ribonucleoprotein complex subunit 4 antibody NAP 57 antibody NAP57 antibody NOLA 4 antibody NOLA4 antibody Nopp140 associated protein of 57 kDa antibody Nopp140-associated protein of 57 kDa antibody Nucleolar protein family A member 4 antibody Nucleolar protein NAP57 antibody snoRNP protein DKC1 antibody XAP 101 antibody XAP101 antibody
Abbreviation
NOLA4
Swiss Prot
O60832 Human, Q9ESX5 Mouse, P40615 Rat
Cellular Locus
Cytoplasm. Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human DKC1 aa 353-402 / 514.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P
Positive Control
A431 cell lysates, A431, human kidney tissue, mouse testis tissue, rat brain tissue, mouse hippocampus tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:100-1:400
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 58 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for DKC1 Recombinant Rabbit Monoclonal Antibody [JU34-32]?

The catalog number for DKC1 Recombinant Rabbit Monoclonal Antibody [JU34-32] is ET7106-93.

What sizes are available for DKC1 Recombinant Rabbit Monoclonal Antibody [JU34-32]?

DKC1 Recombinant Rabbit Monoclonal Antibody [JU34-32] is available in the following size(s): 100 µL.

Is DKC1 Recombinant Rabbit Monoclonal Antibody [JU34-32] in stock?

DKC1 Recombinant Rabbit Monoclonal Antibody [JU34-32] is currently made to order / not held in immediate stock. Contact us for lead time.

What is DKC1 Recombinant Rabbit Monoclonal Antibody [JU34-32] used for?

Isoform 1: Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

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