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Product details

Septin 2 Recombinant Rabbit Monoclonal Antibody [JB41-30]

Catalog number ET7107-05

Price for ET7107-05

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Size / count 100 µL

About this product

Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation . Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein.

Specifications

Catalog number
ET7107-05
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
DIFF6 antibody hNEDD5 antibody KIAA0158 antibody NEDD 5 antibody NEDD5 antibody Neural precursor cell expressed developmentally down regulated 5 antibody Neural precursor cell expressed developmentally down regulated protein 5 antibody Pnutl3 antibody Protein NEDD5 antibody SEPT2 antibody septin 2 antibody
Abbreviation
NEDD-5, SEPT2, DIFF6, KIAA0158, NEDD5
Swiss Prot
Q15019 Human, P42208 Mouse, Q91Y81 Rat
Cellular Locus
Cytoplasm. Cytoskeleton.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Septin 2 aa 182-318 / 361.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
Positive Control
Mouse brain tissue lysate, SiHa cell lysate, K562 cell lysate, HepG2, HUVEC, SH-SY5Y, rat brain tissue, human colon carcinoma tissue, human kidney tissue, K562.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
41 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Septin 2 Recombinant Rabbit Monoclonal Antibody [JB41-30]?

The catalog number for Septin 2 Recombinant Rabbit Monoclonal Antibody [JB41-30] is ET7107-05.

What sizes are available for Septin 2 Recombinant Rabbit Monoclonal Antibody [JB41-30]?

Septin 2 Recombinant Rabbit Monoclonal Antibody [JB41-30] is available in the following size(s): 100 µL.

Is Septin 2 Recombinant Rabbit Monoclonal Antibody [JB41-30] in stock?

Septin 2 Recombinant Rabbit Monoclonal Antibody [JB41-30] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Septin 2 Recombinant Rabbit Monoclonal Antibody [JB41-30] used for?

Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation . Required for normal organization of the actin cytos

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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