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Product details

DDX6 Recombinant Rabbit Monoclonal Antibody [JB41-32]

Catalog number ET7107-06

Price for ET7107-06

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Size / count 100 µL

About this product

RCK, also known as DDX6 and P54, is a member of the DEAD-box RNA helicase family of proteins, all of which share common protein motifs. Found in most tissues, RCK is an unwindase that exhibits ATP-dependent RNA un-winding activity, as well as the ability to decay RNA in the 5'-3' direction. In non-malignant cells, RCK is associated with all processes of normal RNA metabolism including splicing, export and translation initiation. Mutations in the gene encoding RCK can cause the protein to be overexpressed, changing its function to that of an oncogene that positively regulates the expression of genes involved in cell growth and proliferation. It is believed that, through its unwindase activity, the main function of RCK is to downregulate mRNA expression and maintain normal transcriptional levels within the cell.

Specifications

Catalog number
ET7107-06
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
ATP dependent RNA helicase DDX6 antibody ATP dependent RNA helicase p54 antibody DDX6 antibody DEAD (Asp Glu Ala Asp) box polypeptide 6 antibody DEAD box 6 antibody DEAD box protein 6 antibody DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA helicase 54kD) antibody FLJ36338 antibody HLR2 antibody Oncogene RCK antibody P54 antibody Probable ATP-dependent RNA helicase DDX6 antibody RCK antibody
Abbreviation
DDX6, HLR2, RCK
Swiss Prot
P26196 Human, P54823 Mouse
Cellular Locus
Cytoplasm. Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human DDX6 aa 81-220 / 483.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Rat brain tissue, human tonsil tissue, human kidney tissue, mouse small intestine tissue, human colon tissue, SH-SY-5Y, K562, SiHa.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IHC-P: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
54 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for DDX6 Recombinant Rabbit Monoclonal Antibody [JB41-32]?

The catalog number for DDX6 Recombinant Rabbit Monoclonal Antibody [JB41-32] is ET7107-06.

What sizes are available for DDX6 Recombinant Rabbit Monoclonal Antibody [JB41-32]?

DDX6 Recombinant Rabbit Monoclonal Antibody [JB41-32] is available in the following size(s): 100 µL.

Is DDX6 Recombinant Rabbit Monoclonal Antibody [JB41-32] in stock?

DDX6 Recombinant Rabbit Monoclonal Antibody [JB41-32] is currently made to order / not held in immediate stock. Contact us for lead time.

What is DDX6 Recombinant Rabbit Monoclonal Antibody [JB41-32] used for?

RCK, also known as DDX6 and P54, is a member of the DEAD-box RNA helicase family of proteins, all of which share common protein motifs. Found in most tissues, RCK is an unwindase that exhibits ATP-dependent RNA un-winding activity, as well as the ability to decay RNA in the 5'-3' direction. In non-m

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

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