Versican Recombinant Rabbit Monoclonal Antibody [JB42-32]

About this product

Versican (chondroitin sulfate proteoglycan 2) is a large extracellular matrix proteoglycan involved in cell growth and differentiation. Important as a structural molecule, versican creates loose and hydrated matrices during key events in development and disease. The protein contains hyaluronic acid and glycosminoglycan-binding domains, epidermal growth factor-like repeats, a lectin-like sequence and a complement regulatory protein-like domain. Splice variants differ greatly in length and degree of modification by glycosaminoglycan chains. Accumulation around smooth muscle cells in lesions of atherosclerosis, suggests a role for versican in atherogenesis. Versican, differentially expressed in human melanoma, plays a role in tumor development and may be a reliable marker for clinical diagnosis. The organization of HA- and versican-rich pericellular matrices may faciliatate migration and mitosis by diminishing cell surface adhesivity and affecting cell shape through steric exclusion and the viscous properties of HA proteoglycan gels. The human verisican gene maps to chromosome 5q14.3.

Specifications

Catalog number

ET7107-09

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Chondroitin sulfate proteoglycan 2 antibody Chondroitin sulfate proteoglycan core protein 2 antibody Chondroitin sulfate proteoglycan core protein, cartilage antibody CSPG2 antibody CSPG2_HUMAN antibody ERVR antibody GHAP antibody Glial hyaluronate binding protein antibody Glial hyaluronate-binding protein antibody Large fibroblast proteoglycan antibody PG-M antibody PGM antibody VCAN antibody Versican antibody Versican core protein antibody Versican proteoglycan antibody WGN 1 antibody WGN antibody WGN1 antibody

Abbreviation

Chondroitin sulfate proteoglycan 2, GHAP, VCAN, CSPG2

Swiss Prot

P13611 Human, Q62059 Mouse

Cellular Locus

Extracellular matrix. Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human Versican aa 3,160-3,396 / 3,396.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

IHC-P, WB, IF-Tissue

Positive Control

Hela cell lysates, human spleen tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

IHC-P: 1:50-1:1,000 ;WB: 1:1,000 ;IF-Tissue:1;200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

373/265/182/74 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes