LRG1 Recombinant Rabbit Monoclonal Antibody [JB34-31] — image 1 of 2

Product details

LRG1 Recombinant Rabbit Monoclonal Antibody [JB34-31]

Catalog number ET7107-11

Price for ET7107-11

Size / count 100 µL

About this product

Leucine-rich alpha-2-glycoprotein 1 is a protein which in humans is encoded by the gene LRG1. The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation. LRG1 has been shown to be involved in promoting neovascularization (new blood vessel growth) through causing a switch in transforming growth factor beta (TGFbeta) signaling in endothelial cells. LRG1 binds to the accessory receptor endoglin and promotes signaling via the ALK1-Smad1/5/8 pathway. Levels of the LRG protein are markedly elevated in acute appendicitis and therefore could be used as a diagnostic aid. LRG1 may be a potential therapeutic target for the treatment of diseases where there is aberrant neovascularization. Circulating LRG1 levels are increased in many cancer patients and may be a useful biomarker. Inhibition of LRG1 normalises the tumor vasculature, improves the efficacy of cytotoxic and immune therapies,[9] and restricts metastatic spread.

Specifications

Catalog number: ET7107-11
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 1300008B03Rik antibody 2310031E04Rik antibody A2GL antibody A2GL_HUMAN antibody HMFT1766 antibody Leucine rich alpha 2 glycoprotein antibody Leucine-rich alpha-2-glycoprotein 1 antibody Leucine-rich alpha-2-glycoprotein antibody Leucine-rich alpha-2-glycoprotein precursor antibody LRG antibody LRG1 antibody
Abbreviation: LRG, LRG1, LRG
Swiss Prot: P02750 Human
Cellular Locus: Secreted.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human LRG1 aa 261-310 / 347.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IP
Positive Control: Human serum lysates, human kidney tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;IP: 1:10-1:50
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 38 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for LRG1 Recombinant Rabbit Monoclonal Antibody [JB34-31]?

The catalog number for LRG1 Recombinant Rabbit Monoclonal Antibody [JB34-31] is ET7107-11.

What sizes are available for LRG1 Recombinant Rabbit Monoclonal Antibody [JB34-31]?

LRG1 Recombinant Rabbit Monoclonal Antibody [JB34-31] is available in the following size(s): 100 µL.

Is LRG1 Recombinant Rabbit Monoclonal Antibody [JB34-31] in stock?

LRG1 Recombinant Rabbit Monoclonal Antibody [JB34-31] is currently made to order / not held in immediate stock. Contact us for lead time.

What is LRG1 Recombinant Rabbit Monoclonal Antibody [JB34-31] used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.