SMARCC1 Recombinant Rabbit Monoclonal Antibody [JB43-43]

About this product

The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SWI/SNF and contains a predicted leucine zipper motif typical of many transcription factors. Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. May stimulate the ATPase activity of the catalytic subunit of the complex. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.

Specifications

Catalog number

ET7107-12

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

AI115498 antibody BAF 155 antibody BAF155 antibody BRG 1 associated factor 155 antibody BRG1 associated factor 155 antibody BRG1-associated factor 155 antibody Chromatin remodeling complex BAF155 subunit antibody CRACC 1 antibody CRACC1 antibody Mammalian chromatin remodeling complex BRG 1 associated factor 155 antibody Mammalian chromatin remodeling complex BRG1 associated factor 155 antibody Rsc 8 antibody Rsc8 antibody SMARC C1 antibody SMARCC 1 antibody SMARCC1 antibody SMRC1_HUMAN antibody SRG 3 antibody SRG3 antibody SWI 3 antibody SWI/SNF complex 155 kDa subunit antibody SWI/SNF complex subunit SMARCC1 antibody SWI/SNF related matrix associated actin dependent regulator of chromatin c1 antibody SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily c member 1 antibody SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 antibody SWI3 antibody

Abbreviation

BAF155, SMARCC1

Swiss Prot

Q92922 Human, P97496 Mouse

Cellular Locus

Nucleus. Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant protein within Human SMARCC1 aa 680-820 / 1,105.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC, IP

Positive Control

HL-60 cell lysate, mouse thymus tissue lysate, NIH/3T3 cell lysate, 293T, mouse testis tissue, K562, human lymph node tissue, human esophagus tissue, human small intestine tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IF-Cell: 1:50 ;IHC-P: 1:50-1:400 ;FC: 1:500-1:1,000 ;IP: 1:10-1:50

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 123 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes