JAB1 Recombinant Rabbit Monoclonal Antibody [JB34-96]

About this product

COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), also known as COPS5 or Csn5, is a gene conserved from humans to Saccharomyces cerevisiae. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be a coactivator that increases the specificity of JUN/AP1 transcription factors. COP9 constitutive photomorphogenic homolog subunit 5 has been shown to interact with Macrophage migration inhibitory factor, GFER, BCL3, Ubiquitin carboxy-terminal hydrolase L1, S100A7 and C-jun.

Specifications

Catalog number

ET7107-23

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

38 kDa Mov34 homolog antibody COP9 (constitutive photomorphogenic) homolog subunit 5 antibody COP9 constitutive photomorphogenic homolog subunit 5 antibody COP9 signalosome complex subunit 5 antibody COP9 signalosome subunit 5 antibody Cop9 subunit 5 antibody COPS 5 antibody cops5 antibody CSN 5 antibody CSN5 antibody CSN5_HUMAN antibody JAB 1 antibody Jun activation domain binding protein 1 antibody Jun activation domain binding protein antibody Jun activation domain-binding protein 1 antibody MGC3149 antibody MOV 34 antibody MOV34 antibody MOV34 family, 38-KD member antibody SGN 5 antibody SGN5 antibody Signalosome subunit 5 antibody

Abbreviation

SGN5, Signalosome subunit 5, COPS5, CSN5, JAB1

Swiss Prot

Q92905 Human, O35864 Mouse,

Cellular Locus

Cytoplasm. Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human JAB1 aa 1-140 / 334.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Tissue, IHC-P, IP

Positive Control

Mouse testis tissue lysate, PC-3M cell lysate, A549 cell lysate, human kidney tissue, mouse testis tissue, rat brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500;IHC-P: 1:50-1:200;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 38 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes