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Product details

CRM1 Recombinant Rabbit Monoclonal Antibody [JB35-22]

Catalog number ET7107-27

Price for ET7107-27

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Size / count 100 µL

About this product

Protein transport across the nucleus is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Two cytosolic factors centrally involved in the recognition and docking process are the karyopherin alpha1 and karyopherin beta1 subunits. p62 glycoprotein is a nucleoporin that is not only involved in the nuclear import of proteins, but also the export of nascent mRNA strands. NTF2 (nuclear transport factor 2) interacts with nucleoporin p62 as a homodimer composed of two monomers, and may be an obligate component of functional p62. CRM1 has been shown to be an export receptor for leucine-rich proteins that contain the nuclear export signal (NES).

Specifications

Catalog number
ET7107-27
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Chromosome region maintenance 1 protein homolog antibody CRM 1 antibody CRM1 homolog antibody DKFZp686B1823 antibody emb antibody Exp 1 antibody Exp1 antibody Exportin 1 antibody Exportin-1 antibody Exportin1 antibody XPO 1 antibody xpo1 antibody XPO1_HUMAN antibody
Abbreviation
Exp1, XPO1, CRM1
Swiss Prot
O14980 Human, Q6P5F9 Mouse, Q80U96 Rat
Cellular Locus
Nucleus. Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within C-terminal Human CRM1.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control
Hela cell lysate, 293T cell lysate, LOVO, SiHa, A431, human tonsil tissue, human lung carcinoma tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue, K562, human lymph node tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:400;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 123 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CRM1 Recombinant Rabbit Monoclonal Antibody [JB35-22]?

The catalog number for CRM1 Recombinant Rabbit Monoclonal Antibody [JB35-22] is ET7107-27.

What sizes are available for CRM1 Recombinant Rabbit Monoclonal Antibody [JB35-22]?

CRM1 Recombinant Rabbit Monoclonal Antibody [JB35-22] is available in the following size(s): 100 µL.

Is CRM1 Recombinant Rabbit Monoclonal Antibody [JB35-22] in stock?

CRM1 Recombinant Rabbit Monoclonal Antibody [JB35-22] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CRM1 Recombinant Rabbit Monoclonal Antibody [JB35-22] used for?

Protein transport across the nucleus is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Two cytosolic factors centrally in

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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