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Product details

Nesprin 1 Recombinant Rabbit Monoclonal Antibody [JB35-26]

Catalog number ET7107-28

Price for ET7107-28

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Size / count 100 µL

About this product

Enaptin also known as nesprin-1 or synaptic nuclear envelope protein 1 (syne-1) is an actin-binding protein that in humans that is encoded by the SYNE1 gene. This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Enaptin is a nuclear envelope protein found in human myocytes and synapses, which is made up of 8,797 amino acids. Enaptin is involved in the maintenance of nuclear organization and structural integrity, tethering the cell nucleus to the cytoskeleton by interacting with the nuclear envelope and with F-actin in the cytoplasm. Enaptin contains a coiled alpha-helical region and a large beta-sheet region in the upper part and at least four alpha-helices spliced together, indicating the similarity with collagen. The molecular weight of the mature protein is approximately 1,011 kDa, and it has a theoretical pI of 5.38. It has a theoretical Instability Index (II) of 51.63, indicating that it would be unstable in a test tube. The protein's in vivo half-life, the time it takes for half of the amount of protein in a cell to disappear after its synthesis in the cell, is predicted to be approximately 30 hours (in mammalian reticulocytes).

Specifications

Catalog number
ET7107-28
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
8B antibody ARCA1 antibody C6orf98 antibody CPG2 antibody CPG2 full length antibody dJ45H2.2 antibody EDMD4 antibody Enaptin antibody Myne-1 antibody MYNE1 antibody Myocyte nuclear envelope protein 1 antibody Nesp1 antibody Nesprin-1 antibody Nuclear envelope spectrin repeat protein 1 antibody SCAR8 antibody Spectrin repeat containing nuclear envelope 1 antibody Synaptic nuclear envelope protein 1 antibody Synaptic nuclei expressed gene 1 antibody Syne-1 antibody SYNE1 antibody SYNE1_HUMAN antibody SYNE1B antibody
Abbreviation
KASH1, Myne-1, Syne-1, SYNE1, C6orf98, KIAA0796, KIAA1262, KIAA1756, MYNE1
Swiss Prot
Q8NF91 Human, Q6ZWR6 Mouse,
Cellular Locus
Cytoskeleton. Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Nesprin 1 aa 8,241-8,290 / 8,797.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control
A549, mouse spleen tissue lysate, C2C12, HUVEC, rat brain tissue, human tonsil tissue, human colon cancer tissue, human kidney tissue, mouse fallopian tubes tissue, Daudi.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IF-Cell: 1:200-1:1,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 1,011 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Nesprin 1 Recombinant Rabbit Monoclonal Antibody [JB35-26]?

The catalog number for Nesprin 1 Recombinant Rabbit Monoclonal Antibody [JB35-26] is ET7107-28.

What sizes are available for Nesprin 1 Recombinant Rabbit Monoclonal Antibody [JB35-26]?

Nesprin 1 Recombinant Rabbit Monoclonal Antibody [JB35-26] is available in the following size(s): 100 µL.

Is Nesprin 1 Recombinant Rabbit Monoclonal Antibody [JB35-26] in stock?

Nesprin 1 Recombinant Rabbit Monoclonal Antibody [JB35-26] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Nesprin 1 Recombinant Rabbit Monoclonal Antibody [JB35-26] used for?

Enaptin also known as nesprin-1 or synaptic nuclear envelope protein 1 (syne-1) is an actin-binding protein that in humans that is encoded by the SYNE1 gene. This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localiz

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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