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Product details

Furin Recombinant Rabbit Monoclonal Antibody [JB35-53]

Catalog number ET7107-37

Price for ET7107-37

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Size / count 100 µL

About this product

Furin is a protease enzyme that in humans and other animals is encoded by the FURIN gene. Some proteins are inactive when they are first synthesized, and must have sections removed in order to become active. Furin cleaves these sections and activates the proteins. The gene was known as FUR (FES Upstream Region) and therefore the protein was named furin. Furin is also known as PACE (Paired basic Amino acid Cleaving Enzyme). A member of family S8, furin is a subtilisin-like peptidase. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can efficiently cleave precursor proteins at their paired basic amino acid processing sites. Some of its substrates are: proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor.

Specifications

Catalog number
ET7107-37
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Dibasic processing enzyme antibody Dibasic-processing enzyme antibody FES upstream region antibody FUR antibody FURIN antibody Furin membrane associated receptor protein antibody FURIN_HUMAN antibody PACE antibody Paired basic amino acid residue cleaving enzyme antibody Paired basic amino acid residue-cleaving enzyme antibody PCSK3 antibody Proprotein convertase subtilisin/kexin type 3 antibody SPC1 antibody
Abbreviation
PACE, FURIN, FUR, PACE, PCSK3
Swiss Prot
P09958 Human, P23188 Mouse, P23377 Rat
Cellular Locus
Secreted. Plasma membrane. Golgi apparatus. Endosome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Furin aa 261-310 / 794.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
293T cell lysate, A431 cell lysate, C2C12 cell lysate, PC-12 cell lysate, human liver tissue, human colon tissue, human placenta tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IHC-P: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 87 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Furin Recombinant Rabbit Monoclonal Antibody [JB35-53]?

The catalog number for Furin Recombinant Rabbit Monoclonal Antibody [JB35-53] is ET7107-37.

What sizes are available for Furin Recombinant Rabbit Monoclonal Antibody [JB35-53]?

Furin Recombinant Rabbit Monoclonal Antibody [JB35-53] is available in the following size(s): 100 µL.

Is Furin Recombinant Rabbit Monoclonal Antibody [JB35-53] in stock?

Furin Recombinant Rabbit Monoclonal Antibody [JB35-53] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Furin Recombinant Rabbit Monoclonal Antibody [JB35-53] used for?

Furin is a protease enzyme that in humans and other animals is encoded by the FURIN gene. Some proteins are inactive when they are first synthesized, and must have sections removed in order to become active. Furin cleaves these sections and activates the proteins. The gene was known as FUR (FES Upst

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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