TGF alpha Recombinant Rabbit Monoclonal Antibody [JB58-36] — image 1 of 3

Product details

TGF alpha Recombinant Rabbit Monoclonal Antibody [JB58-36]

Catalog number ET7107-40

Price for ET7107-40

Size / count 100 µL

About this product

Transforming growth factor alpha (TGF-α) is a protein that in humans is encoded by the TGFA gene. As a member of the epidermal growth factor (EGF) family, TGF-α is a mitogenic polypeptide. The protein becomes activated when binding to receptors capable of protein kinase activity for cellular signaling. TGF-α is a transforming growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. TGF-α can be produced in macrophages, brain cells, and keratinocytes. TGF-α induces epithelial development. Considering that TGF-α is a member of the EGF family, the biological actions of TGF-α and EGF are similar. For instance, TGF-α and EGF bind to the same receptor. When TGF-α binds to EGFR it can initiate multiple cell proliferation events. Cell proliferation events that involve TGF-α bound to EGFR include wound healing and embryogenesis.

Specifications

Catalog number: ET7107-40
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: EGF like TGF antibody EGF-like TGF antibody ETGF antibody TFGA antibody TGF A antibody TGF type 1 antibody TGF-alpha antibody Tgfa antibody TGFA_HUMAN antibody Transforming growth factor alpha antibody Transforming growth factor alpha precursor antibody Wa1 antibody Waved 1 antibody
Abbreviation: TGF-alpha, ETGF, TGFA
Swiss Prot: P01135 Human
Cellular Locus: Plasma membrane. Extracellular region. Secreted.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human TGF alpha aa 1-160 / 160.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Tissue, IHC-P, IP
Positive Control: MCF7 cell lysate (hot lysis), PANC-1 cell lysate (hot lysis), human liver tissue, human kidney tissue, human tonsil tissue, human colon cancer tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500 ;IF-Tissue: 1:200 ;IHC-P: 1:200-1:1,000 ;IP: 1:50
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 17 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for TGF alpha Recombinant Rabbit Monoclonal Antibody [JB58-36]?

The catalog number for TGF alpha Recombinant Rabbit Monoclonal Antibody [JB58-36] is ET7107-40.

What sizes are available for TGF alpha Recombinant Rabbit Monoclonal Antibody [JB58-36]?

TGF alpha Recombinant Rabbit Monoclonal Antibody [JB58-36] is available in the following size(s): 100 µL.

Is TGF alpha Recombinant Rabbit Monoclonal Antibody [JB58-36] in stock?

TGF alpha Recombinant Rabbit Monoclonal Antibody [JB58-36] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TGF alpha Recombinant Rabbit Monoclonal Antibody [JB58-36] used for?

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.