Biglycan Recombinant Rabbit Monoclonal Antibody [JB71-31] — image 1 of 3

Product details

Biglycan Recombinant Rabbit Monoclonal Antibody [JB71-31]

Catalog number ET7107-48

Price for ET7107-48

Size / count 100 µL

About this product

Biglycan is a small leucine-rich repeat proteoglycan (SLRP) which is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. In humans, biglycan is encoded by the BGN gene[5] which is located on the X chromosome. Biglycan is believed to play a role in the mineralization of bone. Knock-out mice that have had the gene for biglycan suppressed (Bgn -/-) have an osteoporosis-like phenotype with reduced growth rate and lower bone mass than mice that can express biglycan. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity. It has also been reported that the presence of biglycan is necessary for BMP-4 to exert its effects on osteoblasts. There is also evidence that biglycan binds to TGF-beta 1.

Specifications

Catalog number: ET7107-48
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: BGN antibody Biglycan antibody Biglycan proteoglycan antibody Bone/cartilage proteoglycan I antibody Dermatan sulphate proteoglycan I antibody DSPG1 antibody PG S1 antibody PG-S1 antibody PGI antibody PGS1_HUMAN antibody SEMDX antibody SLRR1A antibody Small leucine rich protein 1A antibody
Abbreviation: BGN, SLRR1A
Swiss Prot: P21810 Human, P28653 Mouse
Cellular Locus: Secreted, extracellular space, extracellular matrix.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within Human Biglycan aa 260-368 / 368.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, FC, IP
Positive Control: Mouse skeletal muscle tissue lysates, mouse heart tissue, human kidney tissue, HepG2.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 42 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Biglycan Recombinant Rabbit Monoclonal Antibody [JB71-31]?

The catalog number for Biglycan Recombinant Rabbit Monoclonal Antibody [JB71-31] is ET7107-48.

What sizes are available for Biglycan Recombinant Rabbit Monoclonal Antibody [JB71-31]?

Biglycan Recombinant Rabbit Monoclonal Antibody [JB71-31] is available in the following size(s): 100 µL.

Is Biglycan Recombinant Rabbit Monoclonal Antibody [JB71-31] in stock?

Biglycan Recombinant Rabbit Monoclonal Antibody [JB71-31] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Biglycan Recombinant Rabbit Monoclonal Antibody [JB71-31] used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.