RPA70 Recombinant Rabbit Monoclonal Antibody [JB75-32] — image 1 of 3

Product details

RPA70 Recombinant Rabbit Monoclonal Antibody [JB75-32]

Catalog number ET7107-51

Price for ET7107-51

Size / count 100 µL

About this product

The single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, mitochondria, phages and viruses. Replication protein A (RPA), a highly conserved eukaryotic protein, is a heterotrimeric SSB. RPA plays an important role in DNA replication, recombination and repair. The binding of human RPA (hRPA) to DNA involves molecular polarity in which initial hRPA binding occurs on the 5' side of an ssDNA substrate and then extends in the 3' direction to create a stably bound hRPA. RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair. It can also play a role in telomere maintenance. The RPA 70 kDa subunit binds to ssDNA and mediates interactions with many cellular and viral proteins. The DNA binding domain lies in the middle of RPA 70 kDa subunit and comprises two structurally homologous subdomains oriented in tandem. RPA contains a conserved four cysteine-type zinc-finger motif, which mediates the transition of RPA-ssDNA interaction to a stable RPA-ssDNA complex in a redox-dependent manner.

Specifications

Catalog number: ET7107-51
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Dmrpa1 antibody Drosophila Replication Protein A antibody DRPA antibody HSSB antibody Human single stranded DNA binding protein antibody MST075 antibody MSTP075 antibody p70 antibody REPA1 antibody Replication factor A antibody Replication factor A protein 1 antibody Replication protein A 70 kDa DNA-binding subunit antibody Replication protein A 70kDa DNA binding subunit antibody Replication protein A1 70kDa antibody Replication protein A1 antibody RF A antibody RF-A protein 1 antibody RFA antibody RFA1_HUMAN antibody RP A antibody RP-A p70 antibody RPA 70 antibody RPA antibody rpa1 antibody Single stranded binding protein 70 antibody Single-stranded DNA-binding protein antibody
Abbreviation: RP-A p70, RF-A protein 1, RPA1, REPA1, RPA70
Swiss Prot: P27694 Human
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human RPA70 aa 22-71 / 616.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, FC
Positive Control: Hela cell lysates, A549, LOVO, 293T.
Concentration: 1 mg/mL
Dilution: WB: 1:500;IF-Cell: 1:50-1:100;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 68 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for RPA70 Recombinant Rabbit Monoclonal Antibody [JB75-32]?

The catalog number for RPA70 Recombinant Rabbit Monoclonal Antibody [JB75-32] is ET7107-51.

What sizes are available for RPA70 Recombinant Rabbit Monoclonal Antibody [JB75-32]?

RPA70 Recombinant Rabbit Monoclonal Antibody [JB75-32] is available in the following size(s): 100 µL.

Is RPA70 Recombinant Rabbit Monoclonal Antibody [JB75-32] in stock?

RPA70 Recombinant Rabbit Monoclonal Antibody [JB75-32] is currently made to order / not held in immediate stock. Contact us for lead time.

What is RPA70 Recombinant Rabbit Monoclonal Antibody [JB75-32] used for?

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.