CD3G Recombinant Rabbit Monoclonal Antibody [JB38-29]

About this product

The T cell antigen receptor (TCR) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. Much of this signaling process can be attributed to a multisubunit complex of proteins that associates directly with the TCR. This complex has been designated CD3 (cluster of differentiation 3). It is composed of five invariant polypeptide chains that associate to form three dimers: a heterodimer of gamma and epsilon chains (γε), a heterodimer of delta and epsilon chains (δε) and a homodimer of two zeta chains (ζζ) or a heterodimer of zeta and eta chains (ζη). The ζ and η chains are encoded by the same gene but differ in their carboxyl-terminal ends due to an alternative splicing event. The γ, ε and δ chains each contain a single copy of a conserved immunoreceptor tyrosine-based activation motif (ITAM).

Specifications

Catalog number

ET7107-55

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CD3 gamma antibody CD3-GAMMA antibody CD3g antibody CD3g antigen gamma polypeptide (TiT3 complex) antibody CD3g antigen gamma polypeptide antibody CD3g molecule gamma (CD3 TCR complex) antibody CD3g molecule gamma antibody CD3G_HUMAN antibody FLJ17620 antibody FLJ17664 antibody FLJ79544 antibody FLJ94613 antibody MGC138597 antibody T cell antigen receptor complex gamma subunit of T3 antibody T-cell receptor T3 gamma chain antibody T-cell surface glycoprotein CD3 gamma chain antibody T3G antibody

Abbreviation

CD3G, T3G

Swiss Prot

P09693 Human, P11942 Mouse

Cellular Locus

Cell membrane.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Synthetic peptide within Human CD3G aa 133-182 / 182.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC, IP, IF-Cell

Positive Control

Jurkat cell lysate, MOLT-4 cell lysate, mouse thymus tissue lysate, human tonsil tissue, human spleen tissue, mouse spleen tissue, mouse thymus tissue, Jurkat.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IHC-P: 1:50-1:800 ;FC: 1:1,000 ;IP: Use at an assay dependent concentration. ;IF-Cell: 1:50

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 20 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes