LY75 Recombinant Rabbit Monoclonal Antibody [JB87-35] — image 1 of 3

Product details

LY75 Recombinant Rabbit Monoclonal Antibody [JB87-35]

Catalog number ET7107-58

Price for ET7107-58

Size / count 100 µL

About this product

DEC-205 (LY75, lymphocyte antigen 75, GP200-MR6) is a 1,695 residue (mature form) multilectin receptor that belongs to the MMR (macrophage mannose receptor) family of multidomain molecules. MMR family molecules mediate membrane receptor targeting to endosomes or lysosomes rich in major histocompatibility complex class II (MHC II) products. Expressed in mature dendritic cells (DC), DEC-205 contains an extracellular N-terminal cysteine-rich domain, a fibronectin type II domain, ten C-type carbohydrate recognition domains, a single transmembrane region and a small cytoplasmic C-terminal domain (31 amino acids) containing a tyrosine at 1679. DEC-205 elicits either an agonistic or antagonistic effect on IL-4 function, which is demonstrated by the ability of DEC-205 to imitate IL-4-induced maturation of epithelium or to inhibit IL-4-induced proliferation of T cells, respectively.

Specifications

Catalog number: ET7107-58
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: C-type lectin domain family 13 member B antibody CD 205 antibody CD205 antibody CD205 antigen antibody CLEC 13B antibody CLEC13B antibody DEC 205 antibody DEC-205 antibody DEC205 antibody gp200 antibody gp200 MR6 antibody gp200-MR6 antibody LY 75 antibody Ly-75 antibody LY75 antibody LY75_HUMAN antibody Lymphocyte antigen 75 antibody Renal Cell Carcinoma (gp200) antibody
Abbreviation: Ly-75, LY75, CD205, CLEC13B
Swiss Prot: O60449 Human, Q60767 Mouse
Cellular Locus: Membrane.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within Human LY75 aa 1,560-1,722 / 1,722.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IP
Positive Control: THP-1 cell lysates, human tonsil tissue, human colon carcinoma tissue, human kidney tissue, mouse colon tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 198 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for LY75 Recombinant Rabbit Monoclonal Antibody [JB87-35]?

The catalog number for LY75 Recombinant Rabbit Monoclonal Antibody [JB87-35] is ET7107-58.

What sizes are available for LY75 Recombinant Rabbit Monoclonal Antibody [JB87-35]?

LY75 Recombinant Rabbit Monoclonal Antibody [JB87-35] is available in the following size(s): 100 µL.

Is LY75 Recombinant Rabbit Monoclonal Antibody [JB87-35] in stock?

LY75 Recombinant Rabbit Monoclonal Antibody [JB87-35] is currently made to order / not held in immediate stock. Contact us for lead time.

What is LY75 Recombinant Rabbit Monoclonal Antibody [JB87-35] used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.