Frizzled 8 Recombinant Rabbit Monoclonal Antibody [JB40-16] — image 1 of 3

Product details

Frizzled 8 Recombinant Rabbit Monoclonal Antibody [JB40-16]

Catalog number ET7107-68

Price for ET7107-68

Size / count 100 µL

About this product

Receptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Coreceptor along with RYK of Wnt proteins, such as WNT1.

Specifications

Catalog number: ET7107-68
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Frizzled 8 seven transmembrane spanning receptor antibody frizzled 8, seven transmembrane spanning receptor antibody Frizzled family receptor 8 antibody frizzled homolog 8 (Drosophila) antibody Frizzled homolog 8 antibody Frizzled-8 antibody FZ 8 antibody Fz-8 antibody FZ8 antibody FZD 8 antibody FZD8 antibody FZD8_HUMAN antibody hFZ 8 antibody hFz8 antibody HGNC4046 antibody Homolog of Drosophila Frizzled 8 antibody
Abbreviation: Fz-8, hFz8, FZD8
Swiss Prot: Q9H461 Human, Q61091 Mouse
Cellular Locus: Golgi apparatus. Membrane.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within Human Frizzled 8 aa 561-694 / 694.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Mouse lung tissue lysates, human uterus tissue, human kidney tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 73 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Frizzled 8 Recombinant Rabbit Monoclonal Antibody [JB40-16]?

The catalog number for Frizzled 8 Recombinant Rabbit Monoclonal Antibody [JB40-16] is ET7107-68.

What sizes are available for Frizzled 8 Recombinant Rabbit Monoclonal Antibody [JB40-16]?

Frizzled 8 Recombinant Rabbit Monoclonal Antibody [JB40-16] is available in the following size(s): 100 µL.

Is Frizzled 8 Recombinant Rabbit Monoclonal Antibody [JB40-16] in stock?

Frizzled 8 Recombinant Rabbit Monoclonal Antibody [JB40-16] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Frizzled 8 Recombinant Rabbit Monoclonal Antibody [JB40-16] used for?

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.