eEF1A1 Recombinant Rabbit Monoclonal Antibody [JB44-13]

About this product

The elongation factor-1 complex is composed of two subunits, EF-1 α1 (elongation factor 1-alpha 1) and EF-1 α2 (elongation factor 1-alpha 2), and is responsible for the delivery of aminoacyl tRNAs to the ribosome. EF-1 α1 is expressed predominately in brain, placenta, lung, liver, kidney and pancreas, while EF-1 α2 is highly expressed in heart, brain and skeletal muscle. Both EF-1 α1 and α2 localize to the nucleus and belong to the GTP-binding elongation factor family. The gene encoding EF-1 α2, which maps to human chromosome 20q13.3, may play a role in the development of ovarian cancer, while the EF-1 α1 gene, mapping to chromosome 6Q14.1, is commonly present as an autoantigen in patients with Felty syndrome. Felty syndrome is a disorder characterized by rheumatoid arthritis, a swollen spleen, decreased white blood cell count, and increased susceptibility to infection.

Specifications

Catalog number

ET7107-75

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CCS 3 antibody CCS3 antibody Cervical cancer suppressor 3 antibody chunp6927 antibody CTCL tumor antigen antibody EE1A1 antibody EEF 1 antibody EEF1A antibody eEF1A-1 antibody EEF1A1 antibody EF-1-alpha-1 antibody EF-Tu antibody EF1A antibody EF1a like protein antibody EF1A1_HUMAN antibody Elongation factor 1 alpha subunit antibody Elongation factor 1-alpha 1 antibody Elongation factor Tu antibody Eukaryotic elongation factor 1 A-1 antibody Eukaryotic translation elongation factor 1 alpha 1 antibody Eukaryotic translation elongation factor 1 alpha 1 like 14 antibody Glucocorticoid receptor AF 1 specific elongation factor antibody GRAF 1EF antibody HNGC:16303 antibody ik:tdsubc_2a3 antibody ik:tdsubc_2b3 antibody LENG7 antibody Leukocyte receptor cluster (LRC) member 7 antibody Leukocyte receptor cluster member 7 antibody Prostate tumor inducing protein 1 antibody PTI1 antibody tdsubc_2a3 antibody Translation elongation factor 1 alpha 1 like 14 antibody wu:fa91c07 antibody wu:fa94b03 antibody wu:fi13b09 antibody xx:tdsubc_2a3 antibody xx:tdsubc_2b3 antibody

Abbreviation

EF-1-alpha-1, EF-Tu, eEF1A-1, EEF1A1, EEF1A, EF1A, LENG7

Swiss Prot

P68104 Human, P10126 Mouse, P62630 Rat

Cellular Locus

Cell membrane, Cytoplasm, Membrane, Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human eEF1A1 aa 413-462 / 462.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC, IF-Cell, IF-Tissue

Positive Control

HeLa cell lysate, MCF7 cell lysate, 293T cell lysate, Jurkat cell lysate, HepG2 cell lysate, A431 cell lysate, THP-1 cell lysate, K-562 cell lysate, C2C12 cell lysate, Neuro-2a cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, C6 cell lysate, Rat kidney tissue lysate, human breast cancer tissue, human kidney tissue, mouse kidney tissue, rat kidney tissue, HeLa, C2C12, PC-12.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IF-Cell: 1:100-1:250 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:200-1:1,000 ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 50 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes