KDEL Recombinant Rabbit Monoclonal Antibody [JB42-04] — image 1 of 3

Product details

KDEL Recombinant Rabbit Monoclonal Antibody [JB42-04]

Catalog number ET7107-86

Price for ET7107-86

Size / count 100 µL

About this product

Soluble proteins in the endoplasmic reticulum (ER) contain a specific carboxy terminal sequence KDEL (Lys-Asp-Glu-Leu), and include the coat proteins required for vesicle budding from the ER, proteins that form retrograde vesicles on post-ER compartments, and integral membrane proteins that target vesicles to their correct destination. The retention of these soluble proteins in the ER depends on the interaction of the KDEL sequence with the corresponding KDEL receptor, also designated ERD2, in the Golgi apparatus. When KDEL proteins reach the Golgi complex, they are recognized by the KDEL receptor and transported retrograde in COPI-coated vesicles back to the ER. The small GTPase ADP-ribosylation factor 1 (ARF1), a regulator of vesicle transport, interacts with the KDEL receptor. Subsequently, this interaction allows the KDEL receptor to recruit a GTPase-activating protein (GAP) from the cytosol to membranes, which inactivates ARF1.

Specifications

Catalog number: ET7107-86
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: ER lumen protein retaining receptor 1 antibody ERD2.1 antibody ERD21_HUMAN antibody KDEL endoplasmic reticulum protein retention receptor 1 antibody KDEL receptor 1 antibody Kdelr1 antibody Putative MAPK-activating protein PM23 antibody
Abbreviation: KDEL receptor 1, KDELR1, ERD2.1
Cellular Locus: Endoplasmic reticulum Membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide CSEKDEL.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control: Rat testis tissue lysate, human placenta tissue lysate, mouse testis tissue lysate, 293 cell lysate, A549, HepG2, 293T, human placenta tissue, human stomach carcinoma tissue, mouse small intestine tissue, rat epididymis tissue, human small intestine tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2000 ;IF-Cell: 1:400-1:800 ;IF-Tissue: 1:400-1:800 ;IHC-P: 1:100-1:400 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 25 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for KDEL Recombinant Rabbit Monoclonal Antibody [JB42-04]?

The catalog number for KDEL Recombinant Rabbit Monoclonal Antibody [JB42-04] is ET7107-86.

What sizes are available for KDEL Recombinant Rabbit Monoclonal Antibody [JB42-04]?

KDEL Recombinant Rabbit Monoclonal Antibody [JB42-04] is available in the following size(s): 100 µL.

Is KDEL Recombinant Rabbit Monoclonal Antibody [JB42-04] in stock?

KDEL Recombinant Rabbit Monoclonal Antibody [JB42-04] is currently made to order / not held in immediate stock. Contact us for lead time.

What is KDEL Recombinant Rabbit Monoclonal Antibody [JB42-04] used for?

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.