Cubilin Recombinant Rabbit Monoclonal Antibody [JB42-13]

Catalog number ET7107-88

Price for ET7107-88

Size / count 100 µL

About this product

Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.

Specifications

Catalog number: ET7107-88
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 460 kDa receptor antibody cubilin (intrinsic factor-cobalamin receptor) antibody Cubilin antibody Cubilin precursor antibody Cubn antibody CUBN_HUMAN antibody IFCR antibody Intestinal intrinsic factor receptor antibody intrinsic factor B12-receptor antibody Intrinsic factor-cobalamin receptor antibody Intrinsic factor-vitamin B12 receptor antibody megaloblastic anemia 1 antibody MGA1 antibody
Abbreviation: CUBN, IFCR
Swiss Prot: O60494 Human
Cellular Locus: Plasma membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human Cubilin aa 3,376-3,521 / 3,623.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Human kidney tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 399 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Cubilin Recombinant Rabbit Monoclonal Antibody [JB42-13]?

The catalog number for Cubilin Recombinant Rabbit Monoclonal Antibody [JB42-13] is ET7107-88.

What sizes are available for Cubilin Recombinant Rabbit Monoclonal Antibody [JB42-13]?

Cubilin Recombinant Rabbit Monoclonal Antibody [JB42-13] is available in the following size(s): 100 µL.

Is Cubilin Recombinant Rabbit Monoclonal Antibody [JB42-13] in stock?

Cubilin Recombinant Rabbit Monoclonal Antibody [JB42-13] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cubilin Recombinant Rabbit Monoclonal Antibody [JB42-13] used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.