Thrombomodulin Recombinant Rabbit Monoclonal Antibody [JB48-23] — image 1 of 3

Product details

Thrombomodulin Recombinant Rabbit Monoclonal Antibody [JB48-23]

Catalog number ET7107-92

Price for ET7107-92

Size / count 100 µL

About this product

Thrombomodulin functions as a cofactor in the thrombin-induced activation of protein C in the anticoagulant pathway by forming a 1:1 stoichiometric complex with thrombin. This raises the speed of protein C activation thousandfold. Thrombomodulin-bound thrombin has procoagulant effect at the same time by inhibiting fibrinolysis by cleaving thrombin-activatable fibrinolysis inhibitor (TAFI, aka carboxypeptidase B2) into its active form. Thrombomodulin is a glycoprotein on the surface of endothelial cells that, in addition to binding thrombin, regulates C3b inactivation by factor I. Mutations in the thrombomodulin gene (THBD) have also been reported to be associated with atypical hemolytic-uremic syndrome (aHUS). The antigen described as BDCA-3 has turned out to be identical to thrombomodulin. Thus, it was revealed that this molecule also occurs on a very rare (0.02%) subset of human dendritic cells called MDC2. Its function on these cells is unknown.

Specifications

Catalog number: ET7107-92
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: AHUS 6 antibody AHUS6 antibody BDCA 3 antibody BDCA3 antibody CD 141 antibody CD141 antibody CD141 antigen antibody Fetomodulin antibody Thbd antibody THPH12 antibody THRM antibody Thrombomodulin antibody TM antibody TRBM_HUMAN antibody
Abbreviation: TM, THBD, THRM
Swiss Prot: P07204 Human
Cellular Locus: Membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human Thrombomodulin aa 526-575 / 575.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IP
Positive Control: Human lung cancer tissue, human placenta tissue, A431, human lung tissue, human skin tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;IP: 1:10-1:50
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 60 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Thrombomodulin Recombinant Rabbit Monoclonal Antibody [JB48-23]?

The catalog number for Thrombomodulin Recombinant Rabbit Monoclonal Antibody [JB48-23] is ET7107-92.

What sizes are available for Thrombomodulin Recombinant Rabbit Monoclonal Antibody [JB48-23]?

Thrombomodulin Recombinant Rabbit Monoclonal Antibody [JB48-23] is available in the following size(s): 100 µL.

Is Thrombomodulin Recombinant Rabbit Monoclonal Antibody [JB48-23] in stock?

Thrombomodulin Recombinant Rabbit Monoclonal Antibody [JB48-23] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Thrombomodulin Recombinant Rabbit Monoclonal Antibody [JB48-23] used for?

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.