U1A Recombinant Rabbit Monoclonal Antibody [JB33-48] — image 1 of 3

Product details

U1A Recombinant Rabbit Monoclonal Antibody [JB33-48]

Catalog number ET7107-98

Price for ET7107-98

Size / count 100 µL

About this product

SNRPA (small nuclear ribonucleoprotein polypeptide A), also known as U1A (U1 snRNP protein A), is a component of the RNA spliceosome, a complex of proteins that are required for the precise excision of introns from pre-messenger RNA (pre-mRNA). Localizing to the nucleus, SNRPA contains two RRM (RNA recognition motif) domains, namely RRM1 and RRM2, and RRM1 specifically associates with the stem loop II of U1 snRNA (small nuclear RNA). In addition to functioning as a component of the U1 snRNP, SNRPA negatively regulates polyadenylation of SNRPA pre-mRNA, thereby negatively regulating itself. By inhibiting the addition of a polyA tail that would allow the pre-mRNA to mature, SNRPA causes the nuclear exosome degradation of the SNRPA pre-mRNA. At least 16% of cellular SNRPA also functions in an snRNP-free form (SF-A) that complexes with a group of non-snRNP proteins.

Specifications

Catalog number: ET7107-98
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: fc19d01 antibody Mud1 antibody small nuclear ribonucleoprotein polypeptide A antibody snRNP A antibody snRNP protein A antibody SNRPA antibody SNRPA_HUMAN antibody U1 small nuclear ribonucleoprotein A antibody U1 small nuclear RNP specific A antibody U1 snRNP A antibody U1 snRNP specific protein A antibody U1-A antibody U1A antibody wu:fc19d01 antibody zgc:77810 antibody
Abbreviation: U1 snRNP A, U1-A, U1A, SNRPA
Swiss Prot: P09012 Human, Q62189 Mouse, Q5U214 Rat
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human U1A aa 1-96 / 282.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP
Positive Control: Rat brain tissue lysate, K562 cell lysate, A431 cell lysate, mouse kidney tissue lysate, A549 cell lysates, 293T, SH-SY5Y, SiHa, human lung carcinoma tissue, mouse liver tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;IP: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 31 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for U1A Recombinant Rabbit Monoclonal Antibody [JB33-48]?

The catalog number for U1A Recombinant Rabbit Monoclonal Antibody [JB33-48] is ET7107-98.

What sizes are available for U1A Recombinant Rabbit Monoclonal Antibody [JB33-48]?

U1A Recombinant Rabbit Monoclonal Antibody [JB33-48] is available in the following size(s): 100 µL.

Is U1A Recombinant Rabbit Monoclonal Antibody [JB33-48] in stock?

U1A Recombinant Rabbit Monoclonal Antibody [JB33-48] is currently made to order / not held in immediate stock. Contact us for lead time.

What is U1A Recombinant Rabbit Monoclonal Antibody [JB33-48] used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.