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Product details

CYP26A1 Recombinant Rabbit Monoclonal Antibody [JG33-98]

Catalog number ET7108-02

Price for ET7108-02

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Size / count 100 µL

About this product

The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1, also referred to as retinoic acid-4-hydroxylase, is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor β2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos.

Specifications

Catalog number
ET7108-02
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CP26 antibody CP26A_HUMAN antibody CYP26 antibody CYP26A 1 antibody cyp26a1 antibody Cytochrome P450 26A1 antibody Cytochrome P450 family 26 subfamily A polypeptide 1 antibody Cytochrome P450 retinoic acid-inactivating 1 antibody cytochrome P450, family 26, subfamily A, polypeptide 1 antibody cytochrome P450, subfamily XXVIA, polypeptide 1 antibody Cytochrome P450RAI antibody hP450RAI antibody OTTHUMP00000020102 antibody OTTHUMP00000020103 antibody P450 antibody P450 retinoic acid inactivating 1 antibody P450RAI antibody P450RAI1 antibody Retinoic acid 4 hydroxylase antibody Retinoic acid 4-hydroxylase antibody Retinoic acid metabolizing cytochrome antibody Retinoic acid-metabolizing cytochrome antibody
Abbreviation
Cytochrome P450 26A1, CYP26A1, CYP26, P450RAI1
Swiss Prot
O43174 Human, Q8VIL0 Rat
Cellular Locus
Endoplasmic reticulum, Membrane, Microsome.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within Human CYP26A1 aa 181-470 / 497.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
HepG2 cell lysates, 293 cell lysate, human liver tissue lysate, human liver tissue, human pancreas tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 56 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CYP26A1 Recombinant Rabbit Monoclonal Antibody [JG33-98]?

The catalog number for CYP26A1 Recombinant Rabbit Monoclonal Antibody [JG33-98] is ET7108-02.

What sizes are available for CYP26A1 Recombinant Rabbit Monoclonal Antibody [JG33-98]?

CYP26A1 Recombinant Rabbit Monoclonal Antibody [JG33-98] is available in the following size(s): 100 µL.

Is CYP26A1 Recombinant Rabbit Monoclonal Antibody [JG33-98] in stock?

CYP26A1 Recombinant Rabbit Monoclonal Antibody [JG33-98] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CYP26A1 Recombinant Rabbit Monoclonal Antibody [JG33-98] used for?

The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1, also referred to as retinoic acid-4-hy

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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