ELMO1 Recombinant Rabbit Monoclonal Antibody [JG34-59] — image 1 of 3

Product details

ELMO1 Recombinant Rabbit Monoclonal Antibody [JG34-59]

Catalog number ET7108-06

Price for ET7108-06

Size / count 100 µL

About this product

Elmo (engulfment and cell motility) proteins share similarity to C. elegans CED-12. The C. elegans genes ced-2, ced-5, ced-10 and ced-12, and their mammalian homologs, CRKII, DOCK1, RAC1 and ELMO, mediate cytoskeletal rear-rangements during phagocytosis of apoptotic cells as well as cell motility. Elmo1 associates with DOCK 180 and may influence phagocytosis and effect cell shape changes. Src family kinase-mediated tyrosine phosphorylation of Elmo1 influences signaling through Elmo1/Crk/DOCK 180 pathways. Elmo2 interacts directly with Rho G in a GTP-dependent manner and forms a ternary complex with DOCK 180 to induce activation of Rac 1. The Rho G-Elmo2-DOCK 180 pathway is required for activation of Rac 1 and cell spreading mediated by integrin, as well as for neurite outgrowth induced by nerve growth factor. Elmo3 acts in assocation with DOCK 180 and Crk II and may be required in complex with DOCK 180 to activate Rac/Rho small GTPases.

Specifications

Catalog number: ET7108-06
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CED 12 antibody Ced 12 homolog 1 antibody Ced 12 homolog antibody CED-12 antibody CED12 antibody Ced12 homolog 1 antibody Ced12 homolog antibody ELMO 1 antibody ELMO-1 antibody Elmo1 antibody ELMO1_HUMAN antibody Engulfment and cell motility 1 antibody Engulfment and cell motility protein 1 antibody KIAA0281 antibody MGC126406 antibody Protein ced-12 homolog antibody
Abbreviation: ELMO1, KIAA0281
Swiss Prot: Q92556 Human, Q8BPU7 Mouse, D3ZY46 Rat
Cellular Locus: Cytoplasm, Cell membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human ELMO1 aa 678-727 / 727.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IP
Positive Control: SH-SY5Y cell lysate, Raji cell lysate, Mouse lung tissue lysate, Mouse brain tissue lysate, Rat brain tissue lysate, Rat spleen tissue lysate, human appendix tissue, mouse spleen tissue, rat spleen tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;IP: 1-2μg/sample
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 84 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for ELMO1 Recombinant Rabbit Monoclonal Antibody [JG34-59]?

The catalog number for ELMO1 Recombinant Rabbit Monoclonal Antibody [JG34-59] is ET7108-06.

What sizes are available for ELMO1 Recombinant Rabbit Monoclonal Antibody [JG34-59]?

ELMO1 Recombinant Rabbit Monoclonal Antibody [JG34-59] is available in the following size(s): 100 µL.

Is ELMO1 Recombinant Rabbit Monoclonal Antibody [JG34-59] in stock?

ELMO1 Recombinant Rabbit Monoclonal Antibody [JG34-59] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ELMO1 Recombinant Rabbit Monoclonal Antibody [JG34-59] used for?

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.