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![PRPF8 Recombinant Rabbit Monoclonal Antibody [JG57-38] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8d061270361ea82030/imageurl/et7108-18.webp)
Product details
Catalog number ET7108-18
Price for ET7108-18
Size / count 100 µL
PRP8, also designated pre-mRNA-processing-splicing factor 8, is a highly conserved nuclear protein and a central component of the catalytic core of the spliceosome, where it may be involved in various molecular rearrangements. PRP8, which is widely expressed, plays a role in transesterification reactions that regulate splicesome-induced pre-mRNA splicing. Specifically, PRP8 interacts with the GU dinucleotide at the 5' splice site (5'SS) and forms a specific UV-inducible cross-link. It also interacts functionally with the 3'SS, affecting the efficiency of the second catalytic step. PRP8 may play a role in the first transesterification step, as PRP8 mutations that prohibit negative regulation of PRP28 or PRP44/Brr2 subsequently block U4 activation. In addition, PRP8 interacts with a conserved region of U6 that is instrumental in the formation of the catalytic core of the spliceosome.
The catalog number for PRPF8 Recombinant Rabbit Monoclonal Antibody [JG57-38] is ET7108-18.
PRPF8 Recombinant Rabbit Monoclonal Antibody [JG57-38] is available in the following size(s): 100 µL.
PRPF8 Recombinant Rabbit Monoclonal Antibody [JG57-38] is currently made to order / not held in immediate stock. Contact us for lead time.
PRP8, also designated pre-mRNA-processing-splicing factor 8, is a highly conserved nuclear protein and a central component of the catalytic core of the spliceosome, where it may be involved in various molecular rearrangements. PRP8, which is widely expressed, plays a role in transesterification reac
Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.
