SULT2A1 Recombinant Rabbit Monoclonal Antibody [JG36-18]

About this product

The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones. Members of the three groups comprising this superfamily show selectivity to certain substrate compounds. SULT1 sulfotransferases exhibit N-sulfating activities of carcinogenic heterocyclic amines, and are selective toward phenols, whereas SULT2 enzymes prefer hydroxysteroids and SULT3 family members are selective for N-substituted aryl and alicyclic compounds. SULT2A1 catalyzes the sulfonation of procarcinogen xenobiotics, hydroxysteroids and bile acids, and is highly expressed in adrenal and liver tissues. SULT2A1 plays a role in hepatic cholesterol homeostasis. SULT2B1 consists of two isoforms, SULT2B1a and SULT2B1b, which are transcribed from the same gene by alternative splicing of their first exons. Both isoforms are highly selective for the sulphation of 3b-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA and androstenediol. SULT2B1b is expressed in prostate, skin, placenta and lung.

Specifications

Catalog number

ET7108-26

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Alcohol/hydroxysteroid sulfotransferase antibody Bile salt sulfotranasferase 2A1 antibody Bile salt sulfotransferase antibody Dehydroepiandrosterone sulfotransferase antibody DHEA ST antibody DHEA sulfotranasferase antibody DHEA-ST antibody DHEAS antibody EC 2.8.2.14 antibody Hst antibody hSTa antibody Hydroxysteroid sulfotransferase antibody ST2 antibody ST2A1 antibody ST2A1_HUMAN antibody ST2A3 antibody STD antibody sulfotranasferase, dehydroepiandrosterone-preferring antibody Sulfotransferase 2A1 antibody Sulfotransferase family 2A, dehydroepiandrosterone-preferring, member 1 antibody Sulfotransferase family cytosolic 2A dehydroepiandrosterone (DHEA) preferring member 1 antibody Sult2a1 antibody

Abbreviation

DHEA-ST, HST, ST2A1, SULT2A1, HST, STD

Swiss Prot

Q06520 Human, P52843 Mouse, P15709 Rat

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human SULT2A1 aa 140-285 / 285.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Positive Control

Mouse kidney lysates, human liver lysates, 293T, rat adrenal gland tissue, human liver carcinoma tissue, mouse liver tissue, Hela, human liver tissue, human small intestine tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000;IF-Cell: 1:500-1:2,000;IF-Tissue: 1:500-1:2,000;IHC-P: 1:50-1:200;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

34 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes