WSTF Recombinant Rabbit Monoclonal Antibody [JG36-32]

About this product

Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication.

Specifications

Catalog number

ET7108-32

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

baz1b antibody BAZ1B_HUMAN antibody Bromodomain adjacent to zinc finger domain protein 1B antibody hWALP 2 antibody hWALP-2 antibody hWALP2 antibody transcription factor WSTF antibody Tyrosine-protein kinase BAZ1B antibody WALP-2 antibody WALP2 antibody WBRS 9 antibody WBRS-9 antibody WBRS9 antibody WBSC 10 antibody WBSC-10 antibody WBSC10 antibody WBSCR10 antibody WBSCR9 antibody Williams Beuren syndrome chromosome region 9 protein antibody Williams syndrome transcription factor antibody Williams-Beuren syndrome chromosomal region 10 protein antibody Williams-Beuren syndrome chromosomal region 9 protein antibody WSTF antibody

Abbreviation

BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF

Swiss Prot

Q9UIG0 Human

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human WSTF aa 2-96 / 1,483.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, FC

Positive Control

SiHa lysates, K562.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

171 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes