GEF H1 Recombinant Rabbit Monoclonal Antibody [JG36-46] — image 1 of 3

Product details

GEF H1 Recombinant Rabbit Monoclonal Antibody [JG36-46]

Catalog number ET7108-34

Price for ET7108-34

Size / count 100 µL

About this product

Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. May stimulate instead the cortical activity of Rac. Inactive toward CDC42, TC10, or Ras-GTPases. Forms an intracellular sensing system along with NOD1 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIP2 dependent NF-kappaB signaling pathways activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides through NOD1 that is independent of its GEF activity, but also in the activation of NF-kappaB by Shigella effector proteins (IpgB2 and OspB) which requires its GEF activity and the activation of RhoA.

Specifications

Catalog number: ET7108-34
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: AA408978 antibody ARHG2 antibody ARHG2_HUMAN antibody ARHGEF 2 antibody ARHGEF-2 antibody ARHGEF2 antibody GEF antibody GEF H1 antibody GEF-H1 antibody GEFH1 antibody Guanine nucleotide exchange factor H1 antibody KIAA0651 antibody Lbcl1 antibody Lfc antibody LFP40 antibody MGC95068 antibody Microtubule-regulated Rho-GEF antibody mKIAA0651 antibody P40 antibody Proliferating cell nucleolar antigen p40 antibody Protein GEF-H1 antibody Rho guanine nucleotide exchange factor 2 antibody rho/rac guanine nucleotide exchange factor (GEF) 2 antibody rho/rac guanine nucleotide exchange factor 2 antibody rho/rac guanine nucleotide exchange factor antibody
Abbreviation: GEF-H1, ARHGEF2, KIAA0651, LFP40
Swiss Prot: Q92974 Human, Q60875 Mouse, Q5FVC2 Rat
Cellular Locus: Ruffle membrane, cytoskeleton, spindle, Golgi apparatus, Cytoplasm, tight junction, Cytoplasmic vesicle.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human GEF H1 aa 937-986 / 986.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: 293T cell lysate, A431 cell lysate, SH-SY5Y, HUVEC, human tonsil, mouse testis, rat brain tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 112 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for GEF H1 Recombinant Rabbit Monoclonal Antibody [JG36-46]?

The catalog number for GEF H1 Recombinant Rabbit Monoclonal Antibody [JG36-46] is ET7108-34.

What sizes are available for GEF H1 Recombinant Rabbit Monoclonal Antibody [JG36-46]?

GEF H1 Recombinant Rabbit Monoclonal Antibody [JG36-46] is available in the following size(s): 100 µL.

Is GEF H1 Recombinant Rabbit Monoclonal Antibody [JG36-46] in stock?

GEF H1 Recombinant Rabbit Monoclonal Antibody [JG36-46] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GEF H1 Recombinant Rabbit Monoclonal Antibody [JG36-46] used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.