- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
![p53 DINP1 Recombinant Rabbit Monoclonal Antibody [JG37-64] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea812a6/imageurl/et7108-35.webp)
Product details
Catalog number ET7108-35
Price for ET7108-35
Size / count 100 µL
Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.
The catalog number for p53 DINP1 Recombinant Rabbit Monoclonal Antibody [JG37-64] is ET7108-35.
p53 DINP1 Recombinant Rabbit Monoclonal Antibody [JG37-64] is available in the following size(s): 100 µL.
p53 DINP1 Recombinant Rabbit Monoclonal Antibody [JG37-64] is currently made to order / not held in immediate stock. Contact us for lead time.
Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autopha
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
