SF3B3 Recombinant Rabbit Monoclonal Antibody [JG63-53] — image 1 of 3

Product details

SF3B3 Recombinant Rabbit Monoclonal Antibody [JG63-53]

Catalog number ET7108-36

Price for ET7108-36

Size / count 100 µL

About this product

SF3B is a U2 snRNP-associated protein complex essential for spliceosome assembly. SF3B contains the spliceosomal proteins SAP 49, SAP 130 (also known as SF3B3), SAP 145 and SAP 155. SF3B3, SAP 145 and SAP 155 are present in a protein complex in HeLa nuclear extracts and associate with one another. While SF3B3 and SAP 155 interact with each other (directly or indirectly) within this complex, SAP 49 and SAP 145 are known to interact directly with each other. Unexpectedly, the SAP 49-SAP 145 protein-protein interaction requires the amino-terminus of SAP 49, which contains two RNA-recognition motifs. The observation that SAP 49 and SAP 145 interact directly with both U2 snRNP and the pre-mRNA suggests that this protein complex plays a role in tethering U2 snRNP to the branch site.

Specifications

Catalog number: ET7108-36
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: KIAA0017 antibody Pre mRNA splicing factor SF3b 130 kDa subunit antibody Pre-mRNA-splicing factor SF3b 130 kDa subunit antibody RSE1 antibody SAP 130 antibody SAP130 antibody SF3b130 antibody SF3B3 antibody SF3B3_HUMAN antibody Spliceosome associated protein 130 antibody Spliceosome-associated protein 130 antibody Splicing factor 3b subunit 3 130kD antibody Splicing factor 3B subunit 3 antibody STAF130 antibody
Abbreviation: SF3b130, SF3B3, KIAA0017, SAP130
Swiss Prot: Q15393 Human, Q921M3 Mouse,
Cellular Locus: Nucleus. Spliceosome.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human SF3B3 aa 1061-1217 / 1217.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Jurkat cell lysate, Hela cell lysate, human colon cancer tissue, human kidney tissue, mouse testis tissue, human tonsil tissue, rat brain tissue, LOVO.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000;IF-Cell: 1:50-1:100;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 136 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for SF3B3 Recombinant Rabbit Monoclonal Antibody [JG63-53]?

The catalog number for SF3B3 Recombinant Rabbit Monoclonal Antibody [JG63-53] is ET7108-36.

What sizes are available for SF3B3 Recombinant Rabbit Monoclonal Antibody [JG63-53]?

SF3B3 Recombinant Rabbit Monoclonal Antibody [JG63-53] is available in the following size(s): 100 µL.

Is SF3B3 Recombinant Rabbit Monoclonal Antibody [JG63-53] in stock?

SF3B3 Recombinant Rabbit Monoclonal Antibody [JG63-53] is currently made to order / not held in immediate stock. Contact us for lead time.

What is SF3B3 Recombinant Rabbit Monoclonal Antibody [JG63-53] used for?

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.