WNK1 Recombinant Rabbit Monoclonal Antibody [JG36-91] — image 1 of 3

Product details

WNK1 Recombinant Rabbit Monoclonal Antibody [JG36-91]

Catalog number ET7108-41

Price for ET7108-41

Size / count 100 µL

About this product

Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L. Acts as a scaffold to inhibit SLC4A4, SLC26A6 as well as CFTR activities and surface expression, recruits STK39 which mediates the inhibition.

Specifications

Catalog number: ET7108-41
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Erythrocyte 65 kDa protein antibody HSAN2 antibody HSN2 antibody hWNK1 antibody KDP antibody KIAA0344 antibody Kinase deficient protein antibody MGC163339 antibody MGC163341 antibody p65 antibody PPP1R167 antibody PRKWNK1 antibody Prostate derived sterile 20 like kinase antibody Protein kinase lysine deficient 1 antibody Protein kinase lysine-deficient 1 antibody Protein kinase with no lysine 1 antibody Protein phosphatase 1, regulatory subunit 167 antibody PSK antibody Serine/threonine protein kinase WNK1 1 antibody Serine/threonine protein kinase WNK1 2 antibody Serine/threonine protein kinase WNK1 antibody Serine/threonine-protein kinase WNK1 antibody With no K antibody WNK lysine deficient protein kinase 1 antibody WNK lysine deficient protein kinase 1 isoform antibody WNK1 antibody WNK1_HUMAN antibody
Abbreviation: p65, hWNK1, WNK1, HSN2, KDP, KIAA0344, PRKWNK1
Swiss Prot: Q9H4A3 Human, P83741 Mouse, Q9JIH7 Rat
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human WNK1 aa 33-82 / 2382.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: A549 cell lysates, human skin tissue, human breast cancer tissue, mouse testis tissue, rat kidney tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 225/250/280/300 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for WNK1 Recombinant Rabbit Monoclonal Antibody [JG36-91]?

The catalog number for WNK1 Recombinant Rabbit Monoclonal Antibody [JG36-91] is ET7108-41.

What sizes are available for WNK1 Recombinant Rabbit Monoclonal Antibody [JG36-91]?

WNK1 Recombinant Rabbit Monoclonal Antibody [JG36-91] is available in the following size(s): 100 µL.

Is WNK1 Recombinant Rabbit Monoclonal Antibody [JG36-91] in stock?

WNK1 Recombinant Rabbit Monoclonal Antibody [JG36-91] is currently made to order / not held in immediate stock. Contact us for lead time.

What is WNK1 Recombinant Rabbit Monoclonal Antibody [JG36-91] used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.