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Product details

Mib1 Recombinant Rabbit Monoclonal Antibody [JG69-34]

Catalog number ET7108-43

Price for ET7108-43

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Size / count 100 µL

About this product

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis (By similarity). Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation.

Specifications

Catalog number
ET7108-43
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
DAPK-interacting protein 1 antibody Dip 1 antibody DIP-1 antibody Dip1 antibody E3 ubiquitin protein ligase MIB 1 antibody E3 ubiquitin protein ligase MIB1 antibody E3 ubiquitin-protein ligase mib1 antibody KIAA1323 antibody LVNC7 antibody MIB antibody mib1 antibody MIB1_HUMAN antibody Mind bomb homolog 1 antibody Mindbomb E3 ubiquitin protein ligase 1 antibody Ubiquitin ligase mind bomb antibody Zinc finger ZZ type with ankyrin repeat domain protein 2 antibody ZZANK2 antibody ZZZ6 antibody
Abbreviation
DIP-1, MIB1, DIP1, KIAA1323, ZZANK2
Swiss Prot
Q86YT6 Human, Q80SY4 Mouse
Cellular Locus
Plasma membrane. Cytoplasm. Cytoskeleton.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within Human Mib1 aa 2-93 / 1006.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
SH-SY5Y cell lysates, HUVEC, SH-SY5Y, SiHa, human appendix tissue, human Testis tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 110 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Mib1 Recombinant Rabbit Monoclonal Antibody [JG69-34]?

The catalog number for Mib1 Recombinant Rabbit Monoclonal Antibody [JG69-34] is ET7108-43.

What sizes are available for Mib1 Recombinant Rabbit Monoclonal Antibody [JG69-34]?

Mib1 Recombinant Rabbit Monoclonal Antibody [JG69-34] is available in the following size(s): 100 µL.

Is Mib1 Recombinant Rabbit Monoclonal Antibody [JG69-34] in stock?

Mib1 Recombinant Rabbit Monoclonal Antibody [JG69-34] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Mib1 Recombinant Rabbit Monoclonal Antibody [JG69-34] used for?

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitinatio

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

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