ILF3 Recombinant Rabbit Monoclonal Antibody [JG37-63]

About this product

ILF3 (interleukin enhancer binding factor 3) or TCP80 (translational control protein 80), is a ubiquitously expressed nuclear protein that exists in a heterodimer with NF45. NF90 contains two DRBM (double-stranded RNA (dsRNA-)-binding) domains and one DZF domain and, in association with NF45 primarily participates in the regulation of IL-2 expression by binding to the antigen receptor response element (ARRE) target sequence of the IL-2 enhancer. In neuronal cells, the NF45/NF90 heterodimer can repress human rhinovirus type 2 replication by binding to a 5' untranslated region of the viral RNA that encodes the internal ribosome entry site (IRES). NF45 and NF90 belong to the double-stranded RNA-binding protein family and both are substrates for the dsRNA-activated protein kinase, PKR. Due to alternative splicing events, six isoforms exist for NF90, namely NFAR-2 (or ILF3-E), NFAR-1 (or DRBP76), isoform 3, DRBP76α (or ILF3-A), DRBP76δ (also known as DRBP76γ or ILF3-C) and isoform 6.

Specifications

Catalog number

ET7108-49

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CBTF antibody Double stranded RNA binding protein 76 antibody Double-stranded RNA-binding protein 76 antibody DRBF antibody DRBP76 antibody ILF3 antibody ILF3_HUMAN antibody Interleukin enhancer binding factor 3 antibody Interleukin enhancer-binding factor 3 antibody M phase phosphoprotein 4 antibody M-phase phosphoprotein 4 antibody MPHOSPH4 antibody MPP4 antibody NF AT 90 antibody NF-AT-90 antibody NF110 antibody NF90 antibody NFAR antibody Nuclear factor associated with dsRNA antibody Nuclear factor of activated T cells 90 kDa antibody Nuclear factor of activated T-cells 90 kDa antibody TCP80 antibody Translational control protein 80 antibody

Abbreviation

DRBP76, MPP4, NFAR, NF-AT-90, TCP80, ILF3

Swiss Prot

Q12906 Human, Q9Z1X4 Mouse, Q9JIL3 Rat

Cellular Locus

Cytoplasm. Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human ILF3 aa 2-51 / 894.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IP, IF-Cell, IF-Tissue, IHC-P, FC

Positive Control

Rat heart tissue lysate, 293 cell lysate, A431, SH-ST5Y, SiHa, human tonsil tissue, human colon tissue, human prostate carcinoma tissue, mouse testis tissue, mouse kidney tissue, K562.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100;IP: 1:10-1:50

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 75/76/77/83/95/96kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes