PIST Recombinant Rabbit Monoclonal Antibody [JG79-35]

About this product

PIST (PDZ protein interacting specifically with TC10), also known as GOPC (golgi associated PDZ and coiled-coil motif containing), CAL or FIG, is a 462 amino acid protein that localizes to the cytoplasm, as well as to the membrane of the golgi apparatus and to the cell junction. Expressed ubiquitously and containing one PDZ (DHR) domain, PIST functions as a homooligomer that interacts with a variety of proteins and plays a role in intracellular protein trafficking and degradation. Additionally, PIST is thought to regulate ionic currents via membrane channel modification and may also play a role in autophagy. Chromosomal aberrations in the gene encoding PIST are found in glioblastoma multiform (GBM), a common and aggressive form of brain tumor, suggesting a role for mutated PIST in carcinogenesis. Three isoforms of PIST exist due to alternative splicing events.

Specifications

Catalog number

ET7108-59

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CAL antibody CFTR associated ligand antibody CFTR-associated ligand antibody dJ94G16.2 antibody dJ94G16.2 PIST antibody FIG antibody Fused in glioblastoma antibody Golgi associated PDZ and coiled coil motif containing antibody Golgi associated PDZ and coiled coil motif containing protein antibody Golgi-associated PDZ and coiled-coil motif-containing protein antibody GOPC 1 antibody GOPC antibody GOPC_HUMAN antibody GOPC1 antibody OTTHUMP00000040403 antibody PDZ protein interacting specifically with TC 10 antibody PDZ protein interacting specifically with TC10 antibody PDZ/coiled coil domain binding partner for the rho family GTPase TC 10 antibody PDZ/coiled coil domain binding partner for the rho family GTPase TC10 antibody PIST antibody Protein interacting specifically with Tc 10 antibody Protein interacting specifically with Tc10 antibody

Abbreviation

PIST, GOPC, CAL, FIG

Swiss Prot

Q9HD26 Human, Q8BH60 Mouse

Cellular Locus

Cytoplasm. Golgi apparatus. Plasma membrane.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant protein within Human PIST aa 1-140 / 462.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IP, IHC-P, FC

Positive Control

SiHa cell lysates, HepG2, MCF-7, SKOV-3, human liver carcinoma tissue, human colon tissue, human kidney tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100;IP: 1:10-1:50

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

51 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes