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Product details

GRIM19 Recombinant Rabbit Monoclonal Antibody [JG82-33]

Catalog number ET7108-66

Price for ET7108-66

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Size / count 100 µL

About this product

The GRIM family of proteins appear to be novel types of tumor suppressors. Grim19, which stands for gene associated with retinoic-interferon-induced mortality 19 protein, is also designated cell death-regulatory protein Grim-19 or NADH dehydrogenase ubiquinone 1 alpha subcomplex subunit 13. The Grim19 protein plays two roles within the cell. As a member of the interferon-beta and retinoic acid-induced pathway of cell death, Grim19 induces apoptosis. As part of the mitochondrial complex I, Grim19 is essential for its assembly and electron transfer activity. It transfers electrons to the respiratory chain from NADH and plays a role in the interferon/all-trans-retinoic acid (IFN/RA) cell death pathway. It localizes primarily to the mitochondrion, but may translocate to the nucleus upon IFN/RA treatment. Grim19 may also be useful as a biological marker or target for drug development.

Specifications

Catalog number
ET7108-66
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
2700054G14Rik antibody AU022060 antibody B16.6 antibody CDA016 antibody Cell death regulatory protein antibody Cell death regulatory protein GRIM-19 antibody CGI-39 antibody CGI39 protein antibody CI-B16.6 antibody Complex I-B16.6 antibody FLJ58045 antibody FLJ59191 antibody Gene associated with retinoic and IFN-induced mortality 19 protein antibody Gene associated with retinoic and interferon-induced mortality 19 protein antibody Gene associated with retinoic interferon induced mortality 19 protein antibody GRIM-19 antibody NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 antibody NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 antibody NADH ubiquinone oxidoreductase B16.6 subunit antibody NADH-ubiquinone oxidoreductase B16.6 subunit antibody NDUAD_HUMAN antibody NDUFA13 antibody RGD1565358 antibody
Abbreviation
CI-B16.6, GRIM-19, Gene associated with retinoic and IFN-induced mortality 19 protein, NDUFA13, GRIM19
Swiss Prot
Q9P0J0 Human
Cellular Locus
Mitochondrion. Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human GRIM19 aa 1-144 / 144.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
HeLa cell lysate, Ramos cell lysate, 293T cell lysate, Jurkat cell lysate, MCF7 cell lysate, human kidney tissue, human liver tissue, human prostate cancer tissue, HepG2.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:1,000 ;IF-Cell: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 17 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for GRIM19 Recombinant Rabbit Monoclonal Antibody [JG82-33]?

The catalog number for GRIM19 Recombinant Rabbit Monoclonal Antibody [JG82-33] is ET7108-66.

What sizes are available for GRIM19 Recombinant Rabbit Monoclonal Antibody [JG82-33]?

GRIM19 Recombinant Rabbit Monoclonal Antibody [JG82-33] is available in the following size(s): 100 µL.

Is GRIM19 Recombinant Rabbit Monoclonal Antibody [JG82-33] in stock?

GRIM19 Recombinant Rabbit Monoclonal Antibody [JG82-33] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GRIM19 Recombinant Rabbit Monoclonal Antibody [JG82-33] used for?

The GRIM family of proteins appear to be novel types of tumor suppressors. Grim19, which stands for gene associated with retinoic-interferon-induced mortality 19 protein, is also designated cell death-regulatory protein Grim-19 or NADH dehydrogenase ubiquinone 1 alpha subcomplex subunit 13. The Grim

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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